49ers vs. Cardinals Predictions, Odds & Player Props – Week 4

Jan 14, 2023; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) looks to pass in the first quarter during a wild card game against the Seattle Seahawks at Levi's Stadium.
Image Credit: Cary Edmondson-USA TODAY Sports

Need a 49ers vs. Cardinals prediction? We’ve got what you need, as the Cardinals hit the road to face the 49ers on Sunday, Oct 1 at 4:25 ET. The current total stands at 44, with the 49ers being favored by 14 at home.

49ers vs. Cardinals Odds

  • Spread: 49ers -14
  • Total 44

Game Info

  • Date: Sunday, Oct 1
  • Time: 4:25 ET
  • Location: Levi’s Stadium, Santa Clara CA
  • TV: FOX

Cardinals Betting Trends

  • Over their last five games, the Cardinals have an over/under record of 3-2 and are 4-1 vs. the spread.
  • Arizona has a 1-4 record in their last five road games. In this stretch, they averaged 18 points per game while allowing 23. The team also performed well vs the spread at 3-2.
  • Looking back on the team’s last three games as the underdog, the Cardinals have a straight up record of 1-2. Their record vs the spread in these games was 3-0.

49ers Betting Trends

  • In their last five games, the 49ers have an over/under record of 3-2 and are 5-0 vs. the spread.
  • When looking at their past ten home matchups, San Francisco has an ATS record of 5-4-1 while averaging 25 per game. The team went 7-3 overall in these games.
  • Looking back on the team’s last ten games as the favorite, the 49ers have a straight up record of 10-0. Their record vs the spread in these games was 8-1-1.

Will Arizona Win on the Road?

As week 4 approaches, Arizona is in 4th place in the NFC-West, coming in with an overall record of 1-2. In the NFC, they currently reside in 13th place. The Cardinals have a 3-0 ATS record so far. As we enter week 4, their scoring margin per game is +1.7.

In their most recent game, the Cardinals picked up a 28-16 win over the Cowboys. Going into the game, the Cardinals were actually 11.5-point underdogs. This resulted in an ATS win for the Cardinals. The over/under line for the game was set at 43.5 points, and the final combined total surpassed it with 44 points.

Looking at their performance on offense, Joshua Dobbs threw for 189 yards while completing 81% of his passes. On the ground, the Cardinals rushed the ball 30 times for 222 yards. The team’s third-down performance stood at 5/10.

The Arizona defense has recorded five takeaways this season, which places them 5th in the NFL. In terms of points allowed, their average of 22.3 is 13th in the league while giving up 367.7 yards per contest.

Can the 49ers Hold Strong at Home?

Over the course of three games, the 49ers have put together a record of 3-0. This positions them 1st in the NFC-West and 1st in the NFC. The 49ers have put together a record of 2-0-1 against the spread. This mark has come on an average scoring margin of +16.

In their previous game, the 49ers secured a victory against the Giants, by a score of 30-12. The 49ers were able to cover the spread vs. New York, as they went into the game favored by 10.5. In their most recent game, the over/under line was 43.5 points. By combining for 42 points, the under hit.

Versus the Giants, the 49ers finished with 39 rushing attempts, and Christian McCaffrey led the way with 85 yards. Meanwhile, Brock Purdy had 37 pass attempts, resulting in 310 yards and a passer rating of 111.

Going up against the Cardinals’ offense, the 49ers defense has allowed an average of 14 points per game. So far this season, they are 6th in quarterback hits and have yielded an average of 258.3 yards per contest.

49ers vs. Cardinals Player Prop

Joshua Dobbs comes into the game ranked 23rd among quarterbacks in passing attempts. So far, he has thrown for 549 yards while completing 72.0% of his passes.

Given that he is facing a 49ers defense that has done a good job putting pressure on the quarterback so far, I see Dobbs struggling to deal with the pressure of San Francisco’s front seven. I’m taking the under at 188.5 passing yards.

The Prop: Joshua Dobbs Under 188.5 Passing Yards (-117)

49ers vs. Cardinals Predictions

San Francisco initially opened as 10.5-point favorites on their home turf. The lines have shifted in their favor, now standing at -14.

The Cardinals have played tough in every game up to this point, and they surprised with a victory over the Cowboys last week. However, Arizona is still at a substantial talent disadvantage, especially against the 49ers. San Francisco is unlikely to overlook this game while having. a few extra days to prepare, and I’m betting on the 49ers to run away with this one in the second half.

The Pick: 49ers -14 | -110 at Fanduel Sportsbook

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