Illinois vs. Purdue Predictions, Odds & Picks – Saturday, Nov. 12

Purdue quarterback Aidan O'Connell #16 looks downfield in a 2021 home game.
Image Credit: Zach Bolinger/Icon Sportswire via Getty Images)

Illinois is set to face Purdue on Saturday, Nov. 12. Kickoff is scheduled for noon ET while airing on ESPN2. Illinois enters this game as 6.5-point favorites with the total set at 44.5. How will this one play out? Let’s dive into the Illinois vs. Purdue predictions below.

Illinois vs. Purdue Odds

  • Spread: Illinois -6.5
  • Total: 44.5

Odds complied via Betway Sportsbook. New to Betway? Check out our Betway Sportsbook Review to find out how to redeem a $250 risk-free bet!

Game Info

  • Date:  Saturday, Nov. 12
  • Time: noon ET
  • Location: Memorial Stadium – Champaign, IL
  • TV: ESPN2

Illinois Betting Trends

  • Illinois is 6-3 ATS this season
  • The Over is 2-6-1 in Illinois games this season
  • Illinois is 4-2 ATS as favorites this season
  • Illinois is 5-1 as favorites this season
  • Illinois is 4-2 ATS at home this season

Purdue Betting Trends

  • Purdue is 3-6 ATS this season
  • The Over is 6-3 in Purdue games this season
  • Purdue is 2-3 ATS as underdogs this season
  • Purdue is 2-3 as underdogs this season
  • Purdue is 2-2 ATS on the road this season

Illinois vs. Purdue Predictions

In order to make accurate Illinois vs. Purdue predictions, our sports betting model has sorted through thousands of historical college football games to find similar matchups. We can then draw comparisons and find value based on this analysis. The model found that the spread is cheaper than 77% of the 13 most historically similar matchups.

The Pick: Purdue +6.5 | -110 at FanDuel Sportsbook