Three NFL Player Props For Monday Night Football Week 10

Los Angeles Rams quarterback Matthew Stafford #9 celebrates a touchdown pass in the Rams' 2021 season opening win over the Chicago Bears.
Image Credit: Kirby Lee-USA TODAY Sports

We have one final opportunity to bet in Week 10. With that in mind, I’m going to run through my three favorite NFL player props for Monday Night Football between the Rams and 49ers. Bear in mind that both of these teams are coming off bad losses last time around.

And where there is anger and extra incentive, there are usually better individual performances.

The Rams are currently sitting as a four-point road favorite with an over/under of 49 total points.

All odds courtesy of BetPrep updated 11:00 AM Eastern on November 11, 2021.

Matthew Stafford Vs. San Francisco 49ers

Los Angeles Rams quarterback #9 Matthew Stafford looks downfield in a 2021 home game.
Image Credit: Katelyn Mulcahy/Getty Images

The Prop: Matthew Stafford Passing Yards Total
The Odds: Over 298.5 yards (-116)/Under 298.5 yards (-114)

The biggest problem for the Rams last week against the Titans was keeping Matthew Stafford upright. He had been sacked eight times all season before being sacked by the Tennessee defensive line five times.

And even still, Stafford threw for 294 yards in a game the Rams never really got going.

The 49ers will not be able to apply the same pressure, and not without blitzing. The unique ability the Titans defensive line gives them – pressure up front with a full complement of defensive backs in coverage – is not something San Francisco can do.

Stafford will be back over 300 yards for the sixth time this season, and the Niners will give up a 300-yard passer for the first time since Week 1.

Take Stafford and the over.

Deebo Samuel Vs. Los Angeles Rams

San Francisco wide receiver #19 Deebo Samuel tries to find running room in a 2021 road game.
Image Credit: Raj Mehta-USA TODAY Sports

The Prop: Deebo Samuel vs. Los Angeles Rams
The Odds: Over 76.5 yards (-114)/Under 76.5 yards (-116)

This year, the best wide receiver in football hasn’t been Davante Adams, DeAndre Hopkins, or Tyreek Hill. The two best wide receivers in football are squaring off in this game – Cooper Kupp of the Rams and Deebo Samuel of the 49ers.

Kupp’s over/under is 98.5, which makes for a tight bet. But the over on the 76.5 for Samuel is a good bet.

Samuel is averaging 110 yards receiving per game, and he’s gone over 93 yards in five games this season. He’s been consistently good all season, and the connection that he’s built with quarterback Jimmy Garoppolo is one of the best in the NFL.

The Rams have also proven to be vulnerable to good wide receivers. Kalif Raymond went for 115 yards, Brandin Cooks had 83, DK Metcalf had 98, the Bucs Mike Evans went for 106, and Michael Pittman of the Colts had 123.

All of that together points to Samuel going over 76.5 yards.

Darrell Henderson Vs. San Francisco 49ers

Los Angeles Rams running back #27 Darrell Henderson tries to find running room in a 2021 home game against the Arizona Cardinals.
Image Credit: Harry How/Getty Images

The Prop: Darrell Henderson Total Yards
The Odds: Over 89.5 yards (-115)/Under 89.5 yards (-115)

Darrell Henderson hasn’t been that involved in the passing game recently and hasn’t gone over 20 yards receiving in three straight weeks.

But earlier in the season, he was getting more play out of the backfield and had 29 yards receiving against both the Colts and Giants, and he had 27 yards against the Cardinals.

This week he gets involved again and catches passes for around 25 yards. Add that to the 70 yards per game he is averaging on the ground, and Henderson will get close to 100 total yards.

The 49ers just gave up 173 total yards to James Conner (96 rushings and 77 receiving), and earlier this year, they allowed Jamaal Williams to go for 110 (54 rushings and 56 receiving). Aaron Jones got 96 (82 rushings and 14 receiving).

Henderson’s rushing yards over/under is 70.5, which is a tough bet. But the 89.5 over/under on total yards is a good bet. Take this over.