Cincinnati vs. Louisville Predictions: Fenway Bowl Odds & Picks (Saturday, Dec. 17)

Cincinnati Bearcats running back Ryan Montgomery (22) runs for a touchdown in the third quarter during a college football game against the Tulane Green Wave, Friday, Nov. 25, 2022, at Nippert Stadium in Cincinnati.
Image Credit: Kareem Elgazzar/The Enquirer / USA TODAY NETWORK

It’s the first Saturday of Bowl Season, and the six-game slate starts with Cincinnati vs. Louisville on Saturday, Dec. 17. The game is scheduled for 11 am ET while airing on ESPN. Louisville enters this game as 1.5-point favorites with the total set at 43.5. How will this one play out? Let’s dive into the Cincinnati vs. Louisville predictions as it pertains to the Fenway Bowl odds below.

Fenway Bowl Odds: Cincinnati vs. Louisville

  • Spread: Louisville -1.5
  • Total: 43.5

Odds via PointsBet. New to this sportsbook? Check out our exclusive PointsBet Promo to redeem up to $2,000 in risk-free bets!

Game Info

  • Date: Saturday, Dec. 17
  • Time: 11 am ET
  • Location: Fenway Park – Boston, MA
  • TV: ESPN

Cincinnati Betting Trends

  • Over is 3-0-1 in the Bearcats last 4 non-conference games.
  • The Bearcats are 2-5 ATS in their last 7 bowl games.
  • The Bearcats are 2-6 ATS in their last 8 neutral site games.

Louisville Betting Trends

  • The Cardinals are 4-0 ATS in their last 4 games following a ATS loss.
  • The Cardinals are 4-0 ATS in their last 4 games following a straight up loss.

Cincinnati vs. Louisville Predictions

Well, this is awkward, as Louisville head coach Scott Satterfield left to take the same position at Cincinnati. Both teams will operate with interim head coaches for this matchup.

Louisville QB Malik Cunningham will not play in the Fenway Bowl. RB Tiyon Evans and WR Tyler Hudson are out as well. The Cardinals proved they can get the job done without the first two, as they cruised to a 25-10 win over No. 25 NC State on Nov. 19. Louisville QB Brock Domann has played in the last three games, so it’s not like he’s coming into the Fenway Bowl without a feel for this offense.

However, this game will likely be a defensive battle. Both teams rank in the top 30 for scoring defense and total yards allowed. The Cincinnati offense hasn’t been great down the stretch this season, and there’s a good chance Louisville struggles with the ball while missing its key weapons. This game has a score of 20-17 written all over it. Take the under!

The Pick: Under 43.5 total points | -110 at FanDuel Sportsbook