5 NFL PrizePicks Predictions, Picks & Cheat Sheet For Week 1

Sep 11, 2022; Cincinnati, Ohio, USA; Pittsburgh Steelers wide receiver George Pickens (14) catches a pass during warmups prior to the game against the Cincinnati Bengals at Paycor Stadium.
Image Credit: Katie Stratman-USA TODAY Sports

Our Props analysts uncover the best PrizePicks predictions today so you can maximize your bankroll with 5 of our top PrizePicks picks.

We’ll have an updated version of this PrizePicks cheat sheet for every week of the NFL season.

Best PrizePicks Predictions: Week 1

  • Pick 1: Dak Prescott Over 0.5 Passing Yards
  • Pick 2: George Pickens Over 3 Receptions
  • Pick 3: Tyler Boyd Over 3 Receptions
  • Pick 4: Sam LaPorta Over 3 Receptions
  • Pick 5: Anthony Richardson Over 42.5 Rushing Yards

The rationale for each of these PrizePicks bets is listed below.

Keep in mind that the lines can move quickly on PrizePicks, so there’s a chance not all of these props are available if you are viewing the article later in the day.

Top PrizePicks Predictions For Week 1

Cowboys QB Dak Prescott Over 0.5 Passing Yards

  • This bet is an obvious no-brainer that is a free square available to all PrizePicks users. So lock it in.

Steelers WR George Pickens Over 3 Receptions

  • Pickens averaged 3.05 receptions per game in 17 games last season.
  • The 49ers ranked 20th in passing yards given up to opponents in 2022.
  • Pickens had hauled in at least 3 receptions in 11 of his last 14 games.

Bengals WR Tyler Boys Over 3 Receptions

  • Boyd averaged 3.45 receptions per game in the regular season last year.
  • Caesars has this prop listed at -179 for Over 2.5 but we can get it for -119 at PrizePicks at a very attainable line.
  • Boyd stretches the defense very thin as he was ranked 18th in yards per target last season, so look for Joe Burrow to target him.

Lions TE Sam LaPorta Over 3 Receptions

  • Lock this in for the Thursday Night matchup vs. Chiefs.
  • LaPorta ranked 6th in receiving grade out of TE in his last season at Iowa
  • Caesars has this prop listed at -193 but we can get it for -119 at PrizePicks
  • LaPorta is the obvious replacement for T.J. Hockenson, and brings even more athleticism to what was a lacking TE slot

Colts QB Anthony Richardson Over 42.5 Rushing Yards

  • Richardson ran for 9 touchdowns for Florida last year and boasts a 4.43 40 yard dash speed as he looks to live up to the QB1 role for the Colts
  • Caesars this prop listed at Over 46.5 at -127 so we can get major value at Over 42.5 (-119) at PrizePicks
  • Shane Steichen is the Colts new head coach after moving on from the Eagles. Steichen played a major role in developing Jalen Hurts into the dual threat that Richardson has the potential to be.

Expand Your Horizons With 5 Apps Like PrizePicks

While PrizePicks is a notable platform for fantasy NFL prop bets, it’s not the ultimate destination. In fact, other sites offer attractive bonuses with more favorable lines.

Explore our comprehensive list of Apps Like Prizepicks to see how you can profit on Underdog Fantasy and other lesser-known DFS apps.

Apps Like PrizePicks – Best Daily Fantasy Sites September 2023

These bonuses can give you extra credit for participating in props pick’em contests on other sites, such as Boom Fantasy, ParlayPlay, ThriveFantasy, OwnersBox, and more.

All in all, you can claim up to $1,250 in bonus credit by signing up for these fantasy apps.