The San Francisco Giants and San Diego Padres go head-to-head on June 21 in the second match of a four-game series. The pitching matchup features rookie Ryan Walker for the Giants and veteran Yu Darvish for the Padres.
How will this one play out? Let’s dive into the Giants vs. Padres predictions, odds, and picks below.
Giants vs. Padres Odds
- Moneyline: Padres -125 / Giants +105
- Total: 8
Odds via Bet365. If you are new to Bet365, click our exclusive promo link below to Bet $1 to Get $200 in bonus bets, regardless if you win or lose.
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Game Info
- Date: Wednesday, June 21
- Time: 9:45 pm ET
- Location: Oracle Park – San Francisco, CA
- TV: ESPN+
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Giants Betting Trends
- Giants are 8-0 in their last 8 vs. National League West.
- Over is 6-1 in Giants last 7 overall.
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Padres Betting Trends
- Padres are 7-2 in their last 9 games following a loss.
- Under is 16-7 in Padres last 23 road games.
Giants vs. Padres Predictions
Rookie Ryan Walker, called up by the Giants, has made one start and 4 relief appearances, with an ERA of 1.65 and 15 strikeouts. In a recent game against the Padres, he gave up a home run to Juan Soto and was called for a pitch-clock violation. On the other side, veteran Yu Darvish has a record of 5-5 and an ERA of 4.74 this season.
Offensively, both teams have experienced highs and lows. The Giants rank 14th in MLB, scoring 5 runs per game, while the Padres rank 26th, scoring 4.2 runs per game. Key players like Joc Pederson, LaMonte Wade Jr., and Michael Conforto for the Giants, and Juan Soto for the Padres, have played crucial roles in igniting their respective teams’ offenses.
Giants vs. Padres Picks
The betting prediction for the moneyline is a close call, but the Giants’ recent home success gives them a slight edge. The inconsistent offenses and the pitching matchup lean towards a lower-scoring game, so the under may be the best bet.
The Pick: Giants Moneyline (+105) | Bet $1, Get $200 (win or lose) at Bet365