Pittsburgh at Notre Dame Predictions, Odds & Picks – Saturday, Oct. 28

Notre Dame Fighting Irish head coach Marcus Freeman reacts after a touchdown during the second half against the South Carolina Gamecocks in the 2022 Gator Bowl at TIAA Bank Field.
Image Credit: Matt Pendleton-USA TODAY Sports

The Pittsburgh Panthers (2-5) are set to face off against the Notre Dame Fighting Irish (6-2) this Saturday at Notre Dame Stadium. The Panthers are coming off a narrow loss against Wake Forest, while the Fighting Irish are riding high after a convincing victory over USC. With the Panthers looking to salvage their season and the Fighting Irish aiming to solidify their position in the rankings, this game promises to be a thrilling encounter.

Below, we have your Pittsburgh at Notre Dame predictions, odds, and picks against the spread.

Pittsburgh at Notre Dame Odds Info

Moneyline: Pittsburgh Panthers +650 (BetRivers) / Notre Dame Fighting Irish -1250 (BetRivers)
Spread: -20.5 – Pittsburgh Panthers -110 (BetMGM) / Notre Dame Fighting Irish -110 (BetMGM)
Total: 44.5 – -104 (FanDuel) / -118 (FanDuel)

Game Info

Date: Saturday, Oct. 28
Time: 03:30 PM
Location: Notre Dame Stadium – Notre Dame, IN
TV: NBC

Pittsburgh Panthers Betting Trends

  • On the road, Pittsburgh Panthers are 0 and 3 this season.
  • Against the spread this season, Pittsburgh Panthers are 2 and 5.
  • Against the spread on the road, Pittsburgh Panthers are 0 and 3.

Notre Dame Fighting Irish Betting Trends

  • At home, Notre Dame Fighting Irish are 3 and 1 this season.
  • Against the spread this season, Notre Dame Fighting Irish are 4 and 2.
  • Against the spread at home, Notre Dame Fighting Irish are 2 and 1.

Pittsburgh at Notre Dame Predictions

The Panthers are coming off a 21-17 loss at Wake Forest last Saturday. However, Pitt showed it can still be dangerous, and explosive, topping Louisville by a 38-21 count at Acrisure Stadium as a 7-point underdog. It s the same Cardinals team that topped the Fighting Irish 33-20 the week before. This Panthers offense has been moribund most of the season, going for just 320.4 total yards per game, and 111.1 rushing yards per contest. However, it did top Louisville, a team that beat Notre Dame -20.5 (-110).

On the other hand, Notre Dame rebounded from that setback at Louisville on Oct. 7 with a 48-20 humbling of USC in the shadows of Touchdown Jesus. The Irish have a lone setback on the home ledger, falling to Ohio State on the final play of regulation on Sept. 23, although the Irish covered that game. In fact, Notre Dame is 3-1 against the spread (ATS) at home this season, with the lone non-cover a 41-17 win over Central Michigan on Sept. 16.

The Panthers have a pretty solid defense, ranking 27th in the nation with just 195.3 opponent passing yards per game, so they should be able to hold QB Sam Hartman down somewhat, keeping the Irish within hailing distance. The Irish have cashed the Under in 3 of the past 4 games, and the lone Over is against USC s atrocious defense. The Panthers might not be great offensively, but they can be a pesky defense, especially against the pass.

Pittsburgh at Notre Dame Pick Against the Spread

Notre Dame Fighting Irish are the clear favorites in this matchup. They have a strong home record this season, going 3-1, and have been successful against the spread, with a 4-2 record. Their recent victory over USC, a team that has a notoriously weak defense, demonstrates their offensive prowess. Furthermore, their quarterback, Sam Hartman, is considered one of the nation’s top passers, which could pose a significant challenge for the Panthers’ defense.

On the other hand, the Panthers have struggled this season, particularly on the road where they have not won a single game. Their offense has been lackluster, averaging just 320.4 total yards per game. Despite their solid defense, it may not be enough to hold off the Irish’s strong offense. Considering these factors, along with the fact that the Irish have covered the spread in three of their four home games this season, the smart pick would be Notre Dame Fighting Irish against the Spread.

The Pick: Notre Dame Fighting Irish -20.5 (BetMGM)

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