NFL Player Props: Kittle Highlights Thursday Night Football Props For Week 16

George Kittle #85 of the San Francisco 49ers warms up during pregame warm-ups before the game against the Arizona Cardinals at Levi's Stadium on November 07, 2021 in Santa Clara, California.
Image Credit: Thearon W. Henderson/Getty Images

We have so many great storylines to follow for this week’s Thursday night NFL clash between the Titans and 49ers. Can Tennessee stop the bleeding before it’s too late and hold on to the AFC South? Will the 49ers keep up the hot play and position themselves to make a run through the NFC playoffs? Which players are going to step up and make the difference for their teams? We’ll take a look at the best NFL player props within that.

All odds via BetPrep as of 5 a.m. ET on Dec. 22.

Jimmy Garoppolo Vs. Tennessee Titans

San Francisco quarterback #10 Jimmy Garoppolo looks downfield for a receiver in a 2021 home game.
Image Credit: Ezra Shaw/Getty Image

The Prop: Jimmy Garoppolo Passing Yards
The Odds: Over 265.5 yards (-114)/Under 265.5 yards (-118)

It is not a coincidence that the 49ers getting hot for this run to the postseason is happening alongside Jimmy Garoppolo playing his best football since leading his team to the Super Bowl two years ago.

Because of the ease of the win over Atlanta, he only had 235 passing yards. But in that huge win at the Bengals, he threw for 296 yards, which followed up on his 299 yards against the Seahawks a week earlier.

Mac Jones threw for 310 yards against this Tennessee pass defense. Trevor Siemian had 298 yards. Even Zach Wilson nearly hit the 300-yard mark. For Jimmy G, in a big game for the 49ers, he goes OVER.

Ryan Tannehill Vs. San Francisco 49ers

Tennessee Titans quarterback #17 Ryan Tannehill looks downfield in a 2021 game.
Image Credit: Sam Greenwood/Getty Images

The Prop: Ryan Tannehill Passing Yards
The Odds: Over 229.5 yards (-114)/Under 229.5 yards (-116)

Even without Derrick Henry, the plan for the Titans offense hasn’t changed much. Run the football, and then run it some more. A.J. Brown is back on the practice field, so that could change. But right now, we’re not sure if he’s ready to play or if next week is the more likely scenario.

Regardless, look for Tennessee to continue focusing on the running game, which will keep Ryan Tannehill’s passing yards low. His last three weeks have been 93 yards against New England, 191 vs. Jacksonville, and 153 at Pittsburgh.

Look for another UNDER from Tannehill on Thursday.

Editor’s Note: New to NFL player props? Check out our complete NFL Props Betting Guide to get up to speed! 

George Kittle Vs. Tennessee Titans

George Kittle #85 of the San Francisco 49ers looks on against the Philadelphia Eagles at Lincoln Financial Field on September 19, 2021 in Philadelphia, Pennsylvania.
Image Credit: Mitchell Leff/Getty Images

The Prop: George Kittle Receiving Yards
The Odds: Over 80.5 yards (-110)/Under 80.5 yards (-120)

One of the reasons Jimmy Garoppolo has seen so much success recently is the play of George Kittle. His November was a washout, with games of 50 yards, 34 yards, and 13 yards. But in three December games, Kittle is averaging 141 yards per game with 28 total catches.

Tight ends haven’t had huge games against this Titans defense. Jonnu Smith had 29 yards. Tyler Higbee had 51 yards in Week 9. Travis Kelce had 65 yards back in Week 7. But Kittle has been on fire, and because the Titans have to respect the 49ers run game so much, Kittle will find spaces to operate in the passing game.

This looks like a fourth straight OVER for Kittle.