Cubs vs. Cardinals Predictions, Odds & Picks – Wednesday, May 10

Justin Steele #35 of the Chicago Cubs reacts after the first inning against the Miami Marlins at Wrigley Field on May 05, 2023 in Chicago, Illinois.
(Photo by Quinn Harris/Getty Images)

The Chicago Cubs will host their division rival St. Louis Cardinals on Wednesday, May 10. First pitch is scheduled for 7:40 pm ET while airing on MLB.TV. The Cardinals enter as -115 road favorites on the moneyline with the total set at 8. How will this one play out? Let’s dive into the Cubs vs. Cardinals predictions, odds, and picks below.

Cubs vs. Cardinals Odds

  • Moneyline: Cardinals -115 / Cubs -105
  • Total: 8

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Game Info

  • Date: Wednesday, May 10
  • Time: 7:40 pm ET
  • Location: Wrigley Field – Chicago, IL
  • TV: MLB.TV

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Starting Pitchers

  • Cubs: LHP Justin Steele (5-0, 1.45 ERA)

Steele has been a revelation for the Cubs this season while holding a 1.45 ERA across seven starts. He has not allowed more than two runs in any start this year, holding opponents to one run or fewer in five-of-seven outings.

  • Cardinals: LHP Jordan Montgomery (2-4, 3.29 ERA)

Montgomery has been fantastic on the road this season, allowing just one earned run in 19.2 innings across three road starts. The competition was pretty stiff too, as those games came at the Los Angeles Dodgers, San Francisco Giants, and Milwaukee Brewers.

Cubs Betting Trends

  • Cubs are 7-1 in their last 8 games with the total set at 6.5 or lower.
  • Under is 5-2 in the last 7 meetings in Chicago.

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Cardinals Betting Trends

  • Cardinals are 4-1 in their last 5 vs. National League Central.
  • Over is 6-1 in Cardinals last 7 overall.

Cubs vs. Cardinals Predictions

As you can see in the starting pitcher section above, both of these hurlers mean business. Montgomery is a solid pitcher that has been magnificent on the road this season. Meanwhile, you could argue that Steele has been one of the best pitchers in the National League up to this point.

The Cardinals have sputtered against left-handed starters in recent weeks, as Patrick Sandoval of the Los Angeles Angels and Matthew Boyd of the Detroit Tigers both put together strong outings vs. the Red Birds.

Similar can be said for the Cubs, who were pinned down by southpaws such as Patrick Corbin and Blake Snell over the last week.

The wind is reportedly blowing in from center at Wrigley Field (10 mph), giving us more confidence to take under 8 total runs.

The Pick: Under 8 | -120 at PointsBet