Duke vs. Ohio State Predictions: College Basketball Picks – Wednesday, Nov. 30

Jeremy Roach #3 of the Duke Blue Devils brings the ball up court during the game against the Xavier Musketeers at Moda Center on November 25, 2022 in Portland, Oregon.
Image Credit: Michael Hickey/Getty Images

The ACC-Big Ten Challenge continues, as Duke is set to face Ohio State on Wednesday, Nov. 30. The game is scheduled for 7:15 pm ET while airing on ESPN. Duke enters this game as 5.5-point favorites with the total set at 135.5. How will this one play out? Let’s dive into the Duke vs. Ohio State predictions below.

Duke vs. Ohio State Odds

  • Spread: Duke  -5.5
  • Total: 135.5

Odds via WynnBET. Check out our exclusive WynnBET Promo Code to redeem your $100 risk-free bet today!

Game Info

  • Date: Wednesday, Nov. 30
  • Time: 7:15 pm ET
  • Location: Cameron Indoor Stadium — Durham, NC
  • TV: ESPN

Duke Betting Trends

  • Under is 4-0 in the Blue Devils last 4 overall.
  • Under is 5-0 in the Blue Devils last 5 games vs. a team with a winning % above .600.
  • Over is 9-3 in the Blue Devils last 12 games following a ATS loss.

Ohio State Betting Trends

  • Over is 23-9 in the Buckeyes last 32 road games vs. a team with a winning home record.
  • Over is 5-2 in the Buckeyes last 7 Wednesday games.
  • Under is 5-2 in the Buckeyes last 7 road games.

Duke vs. Ohio State Predictions

This is a nice top-25 matchup to watch on a Wednesday night. Duke checks in ranked 17th in the country while Ohio State is 25th.

The Buckeyes started the season with three easy wins before falling to San Diego State in the Maui Invitational. However, Ohio State quickly bounced back with victories over Cincinnati and Texas Tech, bringing its record to 5-1.

Duke has picked up three wins over opponents outside of the Power 5 conferences. However, it hasn’t been smooth sailing for the Blue Devils when they face the big boys. Duke lost 64-69 to Kansas on Nov. 15. In early-season tournament action, the Blue Devils narrowly beat Oregon State 54-51 and Xavier 71-64 before getting routed 75-56 against Purdue.

So what gives? The home-court advantage will certainly help the Blue Devils, but can this young group be trusted to pull out a win of six or more points? Instead, it’s better to focus on the total in this game. Duke has gone 4-0 to the under in its last three games. Some of them were by a longshot against Power 5 opponents. This Blue Devils team excels at defending and rebounding.

Because of that, let’s take the under for this primetime matchup.

The Pick: Under 135.5 | -110 at WynnBET