5 NFL PrizePicks Predictions, Picks & Cheat Sheet For Week 10

Oct 15, 2023; Tampa, Florida, USA; Detroit Lions wide receiver Amon-Ra St. Brown (14) runs for a touchdown against the Tampa Bay Buccaneers in the second quarter at Raymond James Stadium.
Image Credit: Nathan Ray Seebeck-USA TODAY Sports

For Week 10, our Props analysts have taken a deep dive into the world of NFL PrizePicks predictions to bring you the top five picks of this slate.

We’ll have an updated version of this PrizePicks cheat sheet for every week of the NFL season.

Best PrizePicks Predictions: Week 10

  • Pick 1: Packers RB Aaron Jones Under 58.5 Rushing Yards
  • Pick 2: Bucs RB Rachaad White Under 46.5 Rushing Yards
  • Pick 3: Lions WR Amon-Ra St. Brown Over 80.5 Receiving Yards
  • Pick 4: Browns QB Deshaun Watson Under 211.5 Passing Yards
  • Pick 5: Commanders QB Sam Howell Over 253.5 Passing Yards

The rationale for each of these PrizePicks bets is listed below.

Keep in mind that the lines can move quickly on PrizePicks, so there’s a chance not all of these props are available if you are viewing the article later in the day.

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Top PrizePicks Predictions For Week 10

Packers RB Aaron Jones Under 58.5 Rushing Yards

  • Jone has gone under this line in four of his five games this season.
  • Jones has not been able to eclipse this number against two bottom-five defenses (Chicago and Denver).
  • It is likely Jones will split his yardage through the air and on the ground, making it hard to surpass 58.5.

Bucs RB Rachaad White Under 46.5 Rushing Yards

  • White has gone under this line in five of his eight games this season.
  • White will likely be utilized through the air, taking away some opportunity to gain rushing yards.
  • The Bucs RB faces a Titans defense that has been middle-of-the-pack in terms of rushing yards allowed to running backs this season.

Lions WR Amon-Ra St. Brown Over 80.5 Receiving Yards

  • St. Brown has gone over this line in five of his last six games.
  • He faces a Chargers pass defense that is giving up the most receiving yards in the league per game.
  • St. Brown had three 100+ yard games where he easily surpassed this number.

Browns QB Deshaun Watson Under 211.5 Passing Yards

  • Watson has only surpassed this line against bottom-tier pass defenses like Arizona and Tennessee.
  • When the Browns faced their only defensive challenge in Cincinnati, Watson passed for 154 yards
  • Watson faces the Ravens who are arguably one of the best overall defenses in the league at this point.

Commanders QB Sam Howell Over 253.5 Passing Yards

  • Howell has thrown for 300+ yards in his last two games.
  • Howell has thrown for 397 yards and 290 yards against the best defense he has faced in Philadelphia this season.
  • He faces the Seahawks who are giving up the eighth-most total yards per game.