Independence Bowl: Louisiana vs. Houston Prediction, Odds & Picks (Friday, Dec. 23)

Houston Cougars quarterback Clayton Tune (3) throws a pass during the second quarter against the Temple Owls at TDECU Stadium.
Image Credit: Maria Lysaker-USA TODAY Sports

It’s the Independence Bowl in Shreveport, LA and the Louisiana Rajin’ Cajuns are set to face the Houston Cougars on Friday, Dec. 23. The game is scheduled for 3 pm ET while airing on ESPN. Houston enters this game as 6.5-point favorites with the total set at 56.5. How will this one play out? Let’s dive into the Louisiana vs. Houston prediction below.

Louisiana vs. Houston Odds

  • Spread: Houston -6.5
  • Total: 56.5

Odds via FanDuel Sportsbook. New to FanDuel? Check out our FanDuel Sportsbook Review to find out how to redeem a $2,500 risk-free bet!

Game Info

  • Date: Friday, Dec. 23
  • Time: 3 pm ET
  • Location: Independence Stadium – Shreveport, LA
  • TV: ESPN

Louisiana Betting Trends

  • Ragin’ Cajuns are 9-3 ATS vs. a team with a winning record
  • Over is 6-0 in Ragin’ Cajuns last 6 games following a straight up win.
  • Over is 6-1 in Ragin’ Cajuns last 7 games following a ATS win.

Houston Betting Trends

  • Cougars are 2-5 ATS in their last 7 neutral site games.
  • Over is 4-0 in Cougars last 4 games following a straight up loss.
  • Over is 4-0 in Cougars last 4 non-conference games.

Louisiana vs. Houston Prediction

Houston is an absolute force on offense, ranking 11th in scoring and 17th in total offense. It helps that top WR Nathaniel Dell did not opt-out of this game, giving dynamic QB Clayton Tune his favorite receiver to keep the offense humming. However, the Cougars rank 110th in total defense, so they need to rely on outscoring their opponents.

There’s a good chance that happens against a middle-of-the-road Lousiana team. The Rajin’ Cajuns have struggled against quality offenses this season, giving up 49 points to Florida State and 39 to Southern Miss. There’s a good chance Houston keeps scoring and Louisiana can’t keep up.

If you are into alternate spreads, then taking Houston -10 for plus-money is another reasonable option, but grabbing the Cougars -6.5 is much safer.

The Pick: Houston -6.5 | -110 at FanDuel Sportsbook