College Hoops: Michigan State vs. Indiana Predictions & Odds (Tuesday, Feb. 21)

Michigan State's Joey Hauser, left, celebrates his score with A.J. Hoggard during the first half in the game against Maryland on Tuesday, Feb. 7, 2023, at the Breslin Center in East Lansing.
Image Credit: Nick King/Lansing State Journal / USA TODAY NETWORK

This should be an exciting game in the Big Ten, as Michigan State will host No. 17 Indiana on Tuesday, Feb. 21. The game is scheduled for 9 pm ET while airing on ESPN. Michigan State enters this game as 2.5-point favorites with the total set at 136.5. How will this one play out? Let’s dive into the Michigan State vs. Indiana predictions below.

Michigan State vs. Indiana Odds

  • Spread: Michigan State -2.5
  • Total: 136.5

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Game Info

  • Date: Tuesday, Feb. 21
  • Time: 9 pm ET
  • Location: Breslin Center — East Lansing, MI
  • TV: ESPN

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Michigan State Betting Trends

  • Spartans are 6-1 ATS in their last 7 home games.
  • Spartans are 2-5 ATS in their last 7 games overall.
  • Home team is 26-10 ATS in the last 36 meetings.

Indiana Betting Trends

  • Hoosiers are 2-7 ATS in their last 9 road games.
  • Under is 4-0 in Hoosiers last 4 overall.
  • Hoosiers are 3-7 ATS in their last 10 games following a ATS loss.

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Michigan State vs. Indiana Predictions

Indiana is the better overall team here, but they aren’t favored. Why? First off, it’s extremely difficult to win a road game in the Big Ten. Second, Michigan State needs this win more than Indiana. So how will this one play out?

Take note that the Hoosiers won the first meeting between these teams while beating MSU 82-69 at home. Trayce Jackson-Davis went off in that matchup, scoring 31 points with 15 rebounds. He’ll likely be the focal point of this game once again.

Indiana is one of the most balanced teams in the nation. They rank in the top 40 for all adjusted offense and adjusted defense metrics (per KenPom.com) while holding a respectable rebound rate. The Spartans are a little worse on offense (65th in adjusted offensive efficiency) while ranking 227th in offensive rebound rate. The Hoosiers have been solid all season, and there’s a good chance they grind out another road win here.

The Pick: Indiana moneyline |+135 at BetFred Sportsbook