NFL Betting: Christian McCaffrey Leads Best Running Back Props For Week 12

Christian McCaffrey #22 of the Carolina Panthers looks on during the first half of their game against the Washington Football Team at Bank of America Stadium on November 21, 2021 in Charlotte, North Carolina.
Image Credit: Jared C. Tilton/Getty Images

In Week 11, four running backs went over 100 yards. Jonathan Taylor went off for 185 yards. D’Andre Swift went over 130 for the second consecutive week by piling up 136 yards against Cleveland. In that same game, Nick Chubb ran for 130, and Joe Mixon beat the Raiders with 123. Which running backs are most likely to go off in Week 12 and win you a prop? Let’s take a look at these NFL betting situations for Week 12.

All odds courtesy of BetPrep updated 10:00 AM Eastern on Nov. 24.

Christian McCaffrey Vs. Miami Dolphins

Carolina Panthers running back #22 Christian McCaffrey looks on from the sideline in a 2020 home game.
Image Credit: Jeremy Brevard-USA TODAY Sports

The Prop: Christian McCaffrey Total Yards

The Odds: Over 122.5 yards (-118)/Under 122.5 yards (-114)

Partly because he’s just that good, and partly because he presents a safe and reliable option as Cam Newton works at learning a new offense; look for Christian McCaffrey to have a big day in Miami.

He’s gone over 100 total yards in three straight games, including 161 yards in Carolina’s win at Arizona and 119 yards last week against Washington. As McCaffrey gets further removed from his injury and Newton gets further advanced in the playbook, those numbers will increase.

Plus, the Dolphins have given up big receiving days to running backs Leonard Fournette, Payton Barber, and James White. McCaffrey is better than all of them, and his numbers will reflect it on Sunday.

Jonathan Taylor Vs. Tampa Bay Buccaneers

Jonathan Taylor #28 of the Indianapolis Colts rushes during the first half against the Buffalo Bills at Highmark Stadium on November 21, 2021 in Orchard Park, New York.
Image Credit: Joshua Bessex/Getty Images

The Prop: Jonathan Taylor Rushing Yards

The Odds: Over 86.5 yards (-118)/Under 86.5 yards (-112)

At some point, Jonathan Taylor will not have a great game. It probably won’t be a bad game, but it won’t be an eye-popping game either, which he has on a regular basis. He’s gone over 100 yards rushing in five of his last six games, and he’s averaging 158 yards over the last three weeks.

The Jets and Jags aren’t great defenses, but this past week he ran over one of the best defenses in all of football, the Bills.

The Bucs expect to have Vita Vea back on the defensive line. They’ve also held up well against running backs this season. Only once has a back gone for more than 70 yards against them. So if there was a week for Taylor to hit a wall, this is it. Still, he’s just been so good, and it’s hard to bet against him.

Javonte Williams Vs. Los Angeles Chargers

Running back Javonte Williams #33 of the Denver Broncos carries the ball in the first half during an NFL preseason game against the Seattle Seahawks at Lumen Field on August 21, 2021 in Seattle, Washington. The Denver Broncos beat the Seattle Seahawks 30-3.
Image Credit: Steph Chambers/Getty Images

The Prop: Javonte Williams Rushing Yards

The Odds: Over 52.5 yards (-119)/Under 52.5 yards (-111)

Javonte Williams has 514 yards in his rookie season, and his 5.0 yards per carry leads all rookie running backs, besting the 4.8 put up by Elijah Mitchell and easily beating Najee Harris and his 3.6 ypc.

The Broncos are also figuring out how to work him more into the offense, which will be big this week against the Chargers, the very worst team in the NFL against the run. L.A. gives up 145.1 yards per game on the ground, and eight different running backs have gone for over 70 against them.

This is a perfect matchup for the second-round pick out of North Carolina.