The Louisville Cardinals (10-2) are set to clash with the USC Trojans (7-5) in a highly anticipated showdown. With the Cardinals on a two-game winning streak and the Trojans looking to extend their three-game streak, this matchup promises to be a battle of momentum. Let’s run through our Louisville vs. USC predictions and Holiday Bowl picks below.
Louisville vs. USC Odds
- Moneyline: Louisville -278 (BetRivers) / USC +210 (BetRivers)
- Spread: Louisville -7.5 (FanDuel)
- Total: 57.5 / Over -110 (DraftKings) / Under -110 (DraftKings)
Game Info
- Date: Wednesday, Dec. 27
- Time: 08:00 PM ET
- Location: PETCO Park – San Diego, CA
- TV: FOX
Louisville Cardinals Betting Trends
- On the road, Louisville Cardinals are 2 and 1 this season.
- Against the spread this season, Louisville Cardinals are 6 and 3.
- Against the spread on the road, Louisville Cardinals are 1 and 1.
USC Trojans Betting Trends
- At home, USC Trojans are 4 and 3 this season.
- Against the spread this season, USC Trojans are 3 and 9.
- Against the spread at home, USC Trojans are 2 and 5.
Louisville vs. USC Predictions
The Louisville Cardinals are heading into the game with an impressive 10-2 record, showcasing a potent offense that has consistently put points on the board. The Cardinals’ offense, led by dynamic playmakers, has been a force to reckon with, and they’ll be looking to exploit any weaknesses in the USC defense.
On the other side, the USC Trojans, with a 7-5 record, have had an up-and-down season but are currently riding a wave of success with three consecutive wins. The Trojans’ resilience will be tested against the Cardinals’ high-flying attack.
Defensively, both teams have had their struggles but have also shown the ability to make crucial stops when it matters most. The game could very well come down to key player matchups and which team can better execute their game plan. The battle in the trenches will be crucial, as both offensive lines look to establish dominance and control the tempo of the game.
Louisville vs. USC – Holiday Bowl Pick
The Louisville Cardinals have demonstrated a strong ability to cover the spread this season, boasting a 6-3 record against the spread (ATS), which is significantly better than the USC Trojans’ 3-9 ATS record.
Moreover, the Cardinals are coming into this game with a strong winning streak, which should give them additional confidence and momentum. The Trojans, despite their recent wins, have not been as consistent throughout the season.
The Cardinals’ potent offense is likely to challenge the Trojans’ defense, and if past performances are any indication, Louisville’s ability to execute under pressure will be the deciding factor in covering the spread in this matchup.
The Pick: Louisville Cardinals -7.5 (BetRivers)