College Hoops: Creighton vs. Marquette Predictions, Odds & Picks (Tuesday, Feb. 21)

Creighton Bluejays guard Ryan Nembhard (2) dribbles against the Villanova Wildcats in the second half at CHI Health Center Omaha.
Image Credit: Steven Branscombe-USA TODAY Sports

Here we go with a big game in the Big East Conference, as No. 19 Creighton will host No. 10 Marquette on Tuesday, Feb. 21. The game is scheduled for 8:30 pm ET while airing on FS1. Creighton enters this game as 5.5-point favorites with the total set at 148.5. How will this one play out? Let’s dive into the Creighton vs. Marquette predictions below.

Creighton vs. Marquette Odds

  • Spread: Creighton -5.5
  • Total: 148.5

Odds via Betfred. Click here to redeem our exclusive Betfred Promo Code for $250 in free bets!

Game Info

  • Date: Tuesday, Feb. 21
  • Time: 8:30 pm ET
  • Location: CHI Health Center Omaha — Omaha, NE
  • TV: FS1

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Creighton Betting Trends

  • Bluejays are 2-5 ATS in their last 7 games following a ATS win.
  • Under is 5-2 in Bluejays last 7 overall.
  • Home team is 4-1 ATS in the last 5 meetings.

Marquette Betting Trends

  • Underdog is 6-1 ATS in the last 7 meetings.
  • Golden Eagles are 10-4 ATS in their last 14 games overall.
  • Over is 4-0 in Golden Eagles last 4 games following a ATS loss.

Creighton vs. Marquette Predictions

Creighton has been met with injuries, a tough nonconference schedule, and inconsistencies this season. However, the Bluejays are still an NCAA tournament contender, and they play really well at home. Creighton has won all eight Big East games in Omaha this season, most recently beating Villanova, No. 16 Xavier, and St. John’s.

Marquette won the first matchup between these teams, outlasting Creighton 69-58 at home. However, the Bluejays didn’t have big man Ryan Kalkbrenner, and they have been playing much better since he returned to the lineup. For as good as Marquette has been this season, the Golden Eagles haven’t been great on the road against ranked teams. In fact, Marquette has lost its last three games in that regard: at Providence on Dec. 20, at Xavier on Jan. 15, and at UConn on Feb. 7.

The crowd in the CHI Center will be rocking for this one, and Creighton should come away with a home victory (and cover the spread) in this entertaining battle.

The Pick: Creighton -5.5 | -110 at Betfred Sportsbook