You’re in the right place for Week 12 Monday Night Football prop ladders and predictions. We’ll try and locate 49ers-Panthers props that offer the most value.
Week 12 MNF brings us a matchup between the San Francisco 49ers and Carolina Panthers, and our analyst Justin Bales is here to find us some winners. Let’s dive into a few player props.
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Week 12 Ladders: 49ers/Panthers Props & Predictions
We have a great Monday Night Football game on the board for Week 12 Let’s dive into our top 49ers-Panthers player props!
NEW: Check out our NFL player props odds comparison tool:
| Player |
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AJ Barner
SEA
TE LAR @ SEA
Dec 18
8:15 PM ET
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- | - | - | - | - | - | ||||
Colby Parkinson
LAR
TE LAR @ SEA
Dec 18
8:15 PM ET
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- | - | - | - | - | - | ||||
Cooper Kupp
SEA
WR LAR @ SEA
Dec 18
8:15 PM ET
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- | - | - | - | - | - | ||||
Davis Allen
LAR
TE LAR @ SEA
Dec 18
8:15 PM ET
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- | - | - | - | - | - | ||||
Jaxon Smith-Njigba
SEA
WR LAR @ SEA
Dec 18
8:15 PM ET
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- | - | ||||||||
Kenneth Walker III
SEA
RB LAR @ SEA
Dec 18
8:15 PM ET
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- | - | - | - | - | - | ||||
Kyren Williams
LAR
RB LAR @ SEA
Dec 18
8:15 PM ET
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- | - | - | - | - | - | ||||
Puka Nacua
LAR
WR LAR @ SEA
Dec 18
8:15 PM ET
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- | - | ||||||||
Rashid Shaheed
SEA
WR LAR @ SEA
Dec 18
8:15 PM ET
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- | - | - | - | - | - | ||||
Zach Charbonnet
SEA
RB LAR @ SEA
Dec 18
8:15 PM ET
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- | - | - | - | - | - | - | |||
A.J. Brown
PHI
WR PHI @ WAS
Dec 20
5:00 PM ET
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- | - | - | - | - | - | - | |||
Dallas Goedert
PHI
TE PHI @ WAS
Dec 20
5:00 PM ET
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- | - | - | - | - | - | - | |||
Deebo Samuel Sr.
WAS
WR PHI @ WAS
Dec 20
5:00 PM ET
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- | - | - | - | - | - | - | - | - | |
DeVonta Smith
PHI
WR PHI @ WAS
Dec 20
5:00 PM ET
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- | - | - | - | - | - | - | |||
Grant Calcaterra
PHI
TE PHI @ WAS
Dec 20
5:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Saquon Barkley
PHI
RB PHI @ WAS
Dec 20
5:00 PM ET
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- | - | - | - | - | - | - | |||
Terry McLaurin
WAS
WR PHI @ WAS
Dec 20
5:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Josh Jacobs
GB
RB GB @ CHI
Dec 20
8:20 PM ET
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- | - | - | - | - | - | - | |||
Aaron Jones Sr.
MIN
RB MIN @ NYG
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Brevyn Spann-Ford
DAL
TE LAC @ DAL
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Bucky Irving
TB
RB TB @ CAR
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
CeeDee Lamb
DAL
WR LAC @ DAL
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Chase Brown
CIN
RB CIN @ MIA
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Chig Okonkwo
TEN
TE KC @ TEN
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Chimere Dike
TEN
WR KC @ TEN
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Chris Godwin Jr.
TB
WR TB @ CAR
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Chris Olave
NO
WR NYJ @ NO
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Dalton Kincaid
BUF
TE BUF @ CLE
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Darius Slayton
NYG
WR MIN @ NYG
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Elic Ayomanor
TEN
WR KC @ TEN
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Emeka Egbuka
TB
WR TB @ CAR
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
George Pickens
DAL
WR LAC @ DAL
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Harold Fannin Jr.
CLE
TE BUF @ CLE
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Jake Ferguson
DAL
TE LAC @ DAL
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Jalen McMillan
TB
WR TB @ CAR
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Ja'Marr Chase
CIN
WR CIN @ MIA
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
James Cook
BUF
RB BUF @ CLE
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Jerry Jeudy
CLE
WR BUF @ CLE
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Jordan Addison
MIN
WR MIN @ NYG
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Justin Jefferson
MIN
WR MIN @ NYG
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Khalil Shakir
BUF
WR BUF @ CLE
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Ladd McConkey
LAC
WR LAC @ DAL
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Mike Evans
TB
WR TB @ CAR
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Oronde Gadsden
LAC
TE LAC @ DAL
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Rico Dowdle
CAR
RB TB @ CAR
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Tanner Hudson
CIN
TE CIN @ MIA
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | - | |
Tetairoa McMillan
CAR
WR TB @ CAR
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | ||
Theo Johnson
NYG
TE MIN @ NYG
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
T.J. Hockenson
MIN
TE MIN @ NYG
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Tony Pollard
TEN
RB KC @ TEN
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | - | ||
Travis Kelce
KC
TE KC @ TEN
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Tyrone Tracy Jr.
NYG
RB MIN @ NYG
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Wan'Dale Robinson
NYG
WR MIN @ NYG
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Xavier Worthy
KC
WR KC @ TEN
Dec 21
1:00 PM ET
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- | - | - | - | - | - | - | |||
Bijan Robinson
ATL
RB ATL @ ARI
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | - | - | |
Brenton Strange
JAX
TE JAX @ DEN
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | |||
Brian Thomas Jr.
JAX
WR JAX @ DEN
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | |||
Courtland Sutton
DEN
WR JAX @ DEN
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | |||
Jakobi Meyers
JAX
WR JAX @ DEN
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | |||
Kyle Pitts Sr.
ATL
TE ATL @ ARI
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | - | - | |
Parker Washington
JAX
WR JAX @ DEN
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | |||
Travis Etienne Jr.
JAX
RB JAX @ DEN
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | |||
Trey McBride
ARI
TE ATL @ ARI
Dec 21
4:05 PM ET
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- | - | - | - | - | - | - | - | - | |
Amon-Ra St. Brown
DET
WR PIT @ DET
Dec 21
4:25 PM ET
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- | - | - | - | - | - | - | - | - | |
Brock Bowers
LV
TE LV @ HOU
Dec 21
4:25 PM ET
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- | - | - | - | - | - | - | - | - | |
Jameson Williams
DET
WR PIT @ DET
Dec 21
4:25 PM ET
|
- | - | - | - | - | - | - | - | - | |
Nico Collins
HOU
WR LV @ HOU
Dec 21
4:25 PM ET
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- | - | - | - | - | - | - | - | - | |
Charlie Kolar
BAL
TE NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | - | - | |
Derrick Henry
BAL
RB NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | - | ||
Hunter Henry
NE
TE NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | |||
Kayshon Boutte
NE
WR NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | |||
Mack Hollins
NE
WR NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | |||
Mark Andrews
BAL
TE NE @ BAL
Dec 21
8:20 PM ET
|
- | - | - | - | - | - | - | |||
Rhamondre Stevenson
NE
RB NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | |||
Stefon Diggs
NE
WR NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | |||
TreVeyon Henderson
NE
RB NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | |||
Zay Flowers
BAL
WR NE @ BAL
Dec 21
8:20 PM ET
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- | - | - | - | - | - | - | |||
Christian McCaffrey
SF
RB SF @ IND
Dec 22
8:15 PM ET
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- | - | - | - | - | - | - | - | - | |
George Kittle
SF
TE SF @ IND
Dec 22
8:15 PM ET
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- | - | - | - | - | - | - | - | - |
Christian McCaffrey Receiving Yards Ladder
McCaffrey is one of the best receiving backs in the NFL, and he’s consistently found success in this area. He’s recorded 74 receptions for 732 yards and 5 touchdowns on 89 targets this season. He’s also posted 40+ receiving yards in each of his 11 games in 2025.
San Francisco’s star running back isn’t a typical option out of the backfield. He’s seen plenty of screens behind the line of scrimmage, but he’ll also see targets deeper down the field. Occasionally, the 49ers will take shots to him, which generally isn’t something running backs see.
This isn’t an ideal matchup for McCaffrey. The Carolina Panthers are only giving up 29.4 receiving yards per game to running backs. They’re also giving up 4.9 receptions on 6.4 targets, and McCaffrey will be their hardest challenge to date.
Where to Bet: Christian McCaffrey 40+ receiving yards (-146) through 80+ receiving yards (+470)
George Kittle Receiving Yards Ladder
Kittle’s only played in six games for the San Francisco 49ers this season. He’s dealt with injuries early on, but he looks fully healthy at this point. Overall, he boasts 27 receptions for 251 yards and 5 touchdowns on 29 targets.
The veteran tight end is coming off his best two games of the season. He’s posted 84 and 67 yards over his two games. He also posted 100+ receiving yards in four games last season, flashing that he still comes with tremendous upside when given the targets.
Kittle will face off against the Carolina Panthers, who have struggled against tight ends this season. They’re giving up 5.3 receptions on 6.7 targets per game to the position. The Panthers are also allowing the seventh-most receiving yards (65.3) per game to opposing tight ends.
Where to Bet: George Kittle 50+ receiving yards (-166) through 100+ receiving yards (+520)
Tetairoa McMillan Receiving Yards Ladder
McMillan has flashed incredible talent as a rookie for the Carolina Panthers this season. He’s posted 54 receptions for 748 yards and 4 touchdowns on 86 targets. He hasn’t been the most consistent player on the field, but he boasts high-level upside.
The rookie is coming off his best game of the season in Week 11. He posted 8 receptions for 130 yards and 2 touchdowns on 10 targets against the Atlanta Falcons. He’s also seen games with 100 and 99 yards this season.
McMillan gets a great matchup against the San Francisco 49ers this week. They’re giving up the fourth-most receiving yards (165.1) per game to opposing wide receivers this season. The 49ers are also allowing 13.6 receptions on 19.5 targets per game to the position.
This matchup works well for McMillan, who is a big-play threat. The 49ers are giving up over 12 yards per reception in 2025, and the rookie boasts the ability to cover most of this ladder with one reception.
Where to Bet: Tetairoa McMillan 60+ receiving yards (-152) through 100 receiving yards (+290)
Looking for more player props content? We’ve got you covered all season:
