The 2025 NFL Week 11 Injury Report contains several key players who could significantly impact each team and the betting market.
Our analyst Juan Carlos Blanco analyzes the biggest names dealing with NFL Week 11 injuries.
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NFL Week 11 Injury Report: Key Players
In this article each week, we’ll highlight some noteworthy players who have opened the practice week with an injury designation of some sort and offer some quick hits on the expected impact of their absences, if those come to fruition.
NOTE: This article is posted on Fridays. Make sure to check on the updated injury statuses before locking in your NFL Week 11 plays. Good luck!
Quarterbacks
Jaxson Dart, Giants, OUT (concussion)
Dart exited the Week 10 loss to the Bears with his concussion, and after failing to practice all week, will sit out Sunday’s matchup against the Packers. Russell Wilson handled emergency duty against Chicago but was ineffective, and after already having seen what Wilson can do during his season-opening starting stint, interim head coach and former NFL QB Mike Kafka has opted to turn the offense over to Jameis Winston.
Winston has a well-earned reputation for taking plenty of chances downfield that lead to a fair amount of turnovers, so it will be interesting to see how he manages without his top downfield threat in Darius Slayton (hamstring) against a talented Packers defense surrendering an NFL-low 8.3 yards per completion. Winston hasn’t thrown a pass all season and completed just 61.1% of his passes with a 13:12 TD:INT across 12 games with the Browns last season.
C.J. Stroud, Texans, OUT (concussion)
Stroud once again failed to practice all week after exiting the Week 9 loss to the Broncos early due to a concussion that he suffered on a hit following a scramble, leaving Davis Mills in position for a second consecutive start.
Mills stepped in for Stroud in that Week 9 game and completed 17 of 30 passes for 137 yards while adding seven rushing yards on two carries. He then led the Texans on a furious second-half comeback in his Week 10 start against the Jaguars, throwing for 292 yards with two touchdowns and an interception while adding 20 rushing yards and another score. He now faces a Titans defense surrendering 11.5 yards per completion at home, along with 235.5 passing yards per contest in that split.
Jayden Daniels, Commanders, OUT (elbow)
Daniels remains out as expected with the dislocated elbow he suffered in Week 9 against the Seahawks, and although he won’t need surgery, he’s going to miss multiple games.
Marcus Mariota will therefore draw the start against the Dolphins in Sunday morning’s clash in Madrid after completing 16 of 22 passes for 213 yards with two touchdowns and no interceptions and adding 22 rushing yards during a 44-22 blowout loss to the Lions in Week 10. As was the case in that game, Mariota will go into battle without his top wideout in Terry McLaurin (quadriceps) against a Dolphins defense that’s given up only 182.8 passing yards per game on the road.
Running Backs
J.K. Dobbins, Broncos, OUT (foot)
Dobbins was unable to practice all week and will now miss his first game of the season in Sunday’s showdown against the Chiefs. The veteran has done an effective job helming the Denver backfield up to this point, averaging 5.0 yards per carry on his way to 772 rushing yards while adding 11 receptions through 10 games.
In his stead Sunday, rookie RJ Harvey, who flashed with three total TDs in Week 8 against the Cowboys, is set for lead-back duties, while Tyler Badie and Jaleel McLaughlin rotate in for snaps.
Isiah Pacheco, Chiefs, OUT (knee)
Pacheco will log a second consecutive absence due to his knee injury, leaving the Chiefs backfield in the hands of Kareem Hunt and Brashard Smith once again, with the possibility either Elijah Mitchell or Clyde Edwards-Helaire (if called up from the practice squad Saturday) also rotate in for snaps.
In the Week 9 loss to the Bills before the bye, Hunt led the way with an 11-49-1 rushing line, Smith and Edwards-Helaire combined for 12 yards on five carries, and Mitchell was a healthy scratch.
Bucky Irving, Buccaneers, OUT (foot/shoulder)
Other notable short-term RB injuries to monitor: Justice Hill, Ravens, OUT (toe); Samaje Perine, Bengals, OUT (ankle); Bam Knight, Cardinals, QUESTIONABLE (ankle);
Wide Receivers
Brian Thomas, Jr., Jaguars, QUESTIONABLE (ankle)
Thomas has a chance to return Sunday against the Chargers after a one-game absence due to an ankle injury. The talented wideout was able to log a trio of limited practices this week, but if he returns to action, he’ll now be competing for targets with Jakobi Meyers, who posted a 3-41-0 receiving line in his Jaguars debut in Week 10 against the Texans while Thomas sat out.
While Thomas previously had Travis Hunter alongside him before the rookie’s season-ending knee injury, Meyers is naturally much more experienced and has had another week of practice to learn the offense and build rapport with Trevor Lawrence.
Marvin Harrison, Jr., Cardinals, OUT (appendix)
Harrison failed to practice all week and will log the first absence of his career. The second-year wideout has been averaging 6.9 targets per contest, and his absence naturally has a significant ripple effect on Arizona’s Jacoby Brissett-led air attack.
Brissett’s top three targets in terms of wideouts Sunday against the 49ers line up to be Michael Wilson, Greg Dortch, and Xavier Weaver, as Zay Jones has been placed on injured reserve with an Achilles injury. Additionally, tight end Trey McBride is essentially guaranteed a boost in his already robust workload, while Emari Demercado may also see some extra pass-catching work out of the backfield in a potential starting role, since Bam Knight is questionable due to an ankle injury.
Drake London, Falcons, QUESTIONABLE (illness)
London is far and away Michael Penix’s favorite target, so if he’s out of action Sunday against the Panthers, the impact on Atlanta’s offense will be seismic. London did finish the week with two limited practices after a Wednesday absence, and if he’s sidelined, he leaves behind an average of 10.6 targets per contest.
Darnell Mooney, David Sills, KhaDarel Hodge, and Casey Washington would line up as Penix’s top four WR options in the event of a London absence, while both Bijan Robinson and Kyle Pitts would also be poised to pick up more targets.
Other notable short-term WR injuries to monitor: Terry McLaurin, Commanders, OUT (quadriceps); Chris Godwin, Buccaneers, OUT (lower leg); Tory Horton, Seahawks, OUT (groin); Rashod Bateman, Ravens, OUT (ankle); Darius Slayton, Giants, OUT (hamstring); Davante Adams, Rams, QUESTIONABLE (oblique); Matthew Golden, Packers, QUESTIONABLE (shoulder); Quentin Johnston, Chargers, QUESTIONABLE (shin); Calvin Ridley, Titans, QUESTIONABLE (hamstring)
Tight Ends
Dalton Kincaid, Bills, OUT (hamstring)
Kincaid failed to practice all week with the hamstring issue he suffered in Week 10 against the Dolphins. The talented tight end’s absence, his second of the season, will open the door for the duo of Dawson Knox and Jackson Hawes to handle the position in Sunday’s game against the Buccaneers.
In Kincaid’s Week 6 absence against the Falcons, only Knox cracked the stat sheet with one catch for 19 yards on two targets, although that reception went for a touchdown.
Sam LaPorta, Lions, OUT (back)
LaPorta was unable to practice all week due to his back injury, setting him up for his first absence of 2025. The talented tight end has been averaging 5.4 targets per game, so there should be a slight bump in opportunity for other Detroit pass catchers.
In terms of LaPorta’s direct replacement, Brock Wright, who’s questionable in his own right due to an ankle injury but is believed to have a good chance of play, is expected slot in as the No. 1 tight end, with Ross Dwelley serving as his backup.
Other notable short-term TE injuries to monitor: Hunter Long, Jaguars, OUT (hip); Brock Wright, Lions, QUESTIONABLE (ankle)
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