College Football Week 11 Odds: Two-Way Play On Purdue Vs Ohio State

C.J. Stroud #7 of the Ohio State Buckeyes looks on during a game between the Maryland Terrapins and Ohio State Buckeyes at Ohio Stadium on October 09, 2021 in Columbus, Ohio.
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The college football Week 11 odds board includes a game that, at first blush, looks to be a blowout: Ohio State hosting Purdue. But as the past few weeks have shown, Purdue is the common denominator for killing College Football Playoff dreams.

The Buckeyes hope to avoid the fate that previously befell Iowa and Michigan State.

TwinsSpires Sportsbook trading analyst Zachary Lucas discussed the Ohio State-Purdue contest and more, providing insights on opening/current lines and action in the college football Week 11 betting market. Check back throughout the week for action updates.

College Football Week 11 Odds

Matchup Time Spread Over/Under
Purdue at Ohio State 3:30 p.m. ET Saturday Ohio State -20.5 63.5
Georgia at Tennessee 3:30 p.m. ET Saturday Georgia -20 55
Washington State at Oregon 10:30 p.m. ET Saturday Oregon -13 57.5
Cincinnati at South Florida 6 p.m. ET Friday Cincinnati -23 57
Oklahoma at Baylor Noon ET Saturday Oklahoma -6 62
Michigan at Penn State Noon ET Saturday Michigan -1 48.5
Mississippi State at Auburn Noon ET Saturday Auburn -5 50
Notre Dame at Virginia 7:30 p.m. ET Saturday Notre Dame -8 62.5
Texas A&M at Mississippi 7 p.m. ET Saturday Texas A&M -2.5 57.5
North Carolina State at Wake Forest 7:30 p.m. ET Saturday Wake Forest -1 65

Odds via TwinSpires Sportsbook and updated as of 5 p.m. ET Nov. 13

Washington State at Oregon

Oregon running back Travis Dye celebrates his second quarter touchdown against Colorado
Image Credit: Chris Pietsch-The Register-Guard/USA TODAY Network

Opening line: Oregon -14, Over/Under 56.5

UPDATE 8 P.M. ET SATURDAY: With kickoff 2.5 hours out, Oregon is down to -12.5 at BetMGM Nevada, after starting today at -14. The Ducks opened -13.5 and went to -14 late Monday night, then made stops earlier today at -13.5 and -13 on the way to the current number.

“We need Oregon. Washington State is a popular play, and there’s some sharp money on the Cougars, too,” BetMGM Nevada’s Jeff Stoneback said. “Tickets are dead even, but money is 3/1 Washington State.”

The total opened at 56.5, initially fell to 56 and has been stable at 57.5 since Thursday evening.

Previous Washington State vs Oregon Odds Updates

UPDATE 8 P.M. ET FRIDAY: Oregon is up to a full two-touchdown favorite at WynnBet, after opening -13. The Ducks are drawing 57% of tickets and 71% of money on the point spread. The total opened and is currently at 57, with 69% of tickets on the Over, but 92% of money on the Under.

UPDATE 3 P.M. ET THURSDAY: DraftKings pegged Oregon as a 14-point favorite Sunday and held firm until Wednesday afternoon, when it dipped to -13.5. And the betting splits are interesting: Underdog Washington State — which has covered the spread in six consecutive games — is taking 81% of tickets, while money is running both ways, with a slight lean toward Oregon at 52%. The total is up a point to 57.5, with 62% of tickets/60% of cash on the Over.

UPDATE 2:30 P.M. ET MONDAY: Oregon (8-1 SU, 3-6 ATS) aims to keep its position among the top four in the CFP rankings. The Ducks took care of Washington 26-16 as 7-point road favorites in Week 10, while Washington State enjoyed a bye after going to Arizona State as a 16.5-point pup and springing the outright upset 34-21 in Week 9. In fact, the Cougars (5-4 SU, 6-3 ATS) have covered six in a row.

Oregon inched off the key number at TwinSpires, moving to -13.5, although 79% of early bets/72% of early dollars are on the Ducks.

“The public is all over Oregon. Sharp play on Washington State +14,” Lucas said.

The total nudged to 57, with 74% of bets/64% of money on the Over.

Purdue at No. 6 Ohio State

Ohio State Buckeyes wide receiver Chris Olave runs the ball after a reception
Image Credit: Joshua A. Bickel/Columbus Dispatch-USA TODAY Network

Opening line: Ohio State -20, Over/Under 61

UPDATE NOON ET SATURDAY: Ohio State moved from -20 to -21 by midweek at PointsBet USA, then receded to -20.5 this morning. Ticket count is 3/1 on the Buckeyes, but money is almost dead even, at 51% on the underdog Boilermakers. The total is up 1.5 points just today, from 63.5 to 65, after opening at 61, with ticket count 2/1 and money almost 5/1 on the Over.

Previous Purdue vs Ohio State Odds Updates

UPDATE 8 P.M. ET FRIDAY: WynnBet pegged Ohio State a 20-point chalk to open and is now up a tick to -20.5. Ticket count is 5/1 on Purdue, with the bulk of bettors taking the points, but money is 2/1 on Ohio State. The total is also up a half-point from the opener, from 63 to 63.5, with 81% of tickets/61% of money on the Over.

UPDATE 3 P.M. ET THURSDAY: Ohio State is up to -21 from a -19 opener at DraftKings. However, the betting splits show the betting public’s affinity to take all those points with Purdue: The Boilermakers are collecting 88% of spread tickets and 75% of spread dollars. The total dropped from 62 to 61 early in the week, but is now up to 63. The Over is taking 62% of tickets/91% of money.

UPDATE 2:30 P.M. ET MONDAY: In Week 7, unranked Purdue went to Iowa as an 11-point underdog and thumped the previously unbeaten Hawkeyes 24-7. Iowa is no longer in the CFP conversation.

Then this past Saturday, unranked Purdue (6-3 SU, 5-4 ATS) never trailed against undefeated and No. 5 Michigan State, winning 40-29 as a 2.5-point home ‘dog. The Spartans, who sat No. 3 in the initial CFP rankings, will certainly fall multiple spots in Tuesday night’s update.

While Ohio State is a much larger favorite at Purdue this week, those results have to give the Buckeyes pause. In Week 10, Ohio State (8-1 SU, 4-4-1 ATS) struggled to get past Nebraska 26-17, failing to cash as a 14-point road favorite.

TwinSpires’ near-three touchdown spread dipped to Buckeyes -19.5 this afternoon, with early ticket count and money in the 2/1 range on underdog Purdue.

“The public is grabbing the points so far in this matchup,” Lucas said.

The total is already up to 62.5, with 62% of tickets/74% of money on the Over.

No. 1 Georgia at Tennessee

Georgia Bulldogs running back Zamir White on the left celebrates with Georgia Bulldogs tight end Brock Bowers on the right after scoring a touchdown
Image Credit: John Reed-USA TODAY Sports

Opening line: Georgia -20.5, Over/Under 55

UPDATE NOON ET SATURDAY: Georgia opened -20.5, went to -20 Thursday and then to -19.5 this morning at PointsBet USA. The Bulldogs are netting 60% of spread bets, while the Vols are taking 58% of spread dollars. The total opened at 55 and has been at 56 since Monday afternoon, with 63% of tickets/75% of money on the Over.

Previous Georgia vs Tennessee Odds Updates

UPDATE 8 P.M. ET FRIDAY: After opening at -18, Georgia is a 20-point favorite tonight at WynnBet. The Bulldogs are taking 62% of spread bets and 75% of spread dollars. The total moved from 53.5 to 55, with the Over taking a heavy majority 88% of bets/87% of dollars on the Over.

UPDATE 3 P.M. ET THURSDAY: Georgia moved from -19.5 to -20.5 within a few hours Sunday at DraftKings, then ticked to -20 Monday and stuck there. The Bulldogs are drawing 55% of tickets and 65% of money on the spread. The total went from 55 to 56 Monday afternoon and remains 56 now, with ticket count 2/1 and money 3/1 on the Over.

UPDATE 2:30 P.M. ET MONDAY: With another big spread on the college football Week 11 odds board, it’s worth pointing out that a few games in this report are only included because of CFP ramifications. This is one such matchup. Georgia (9-0 SU, 6-3 ATS) dunked Missouri 43-6 in Week 10, though it fell short of cashing as a massive 40.5-point home chalk.

Later in the day, Tennessee (5-4 SU, 4-5 ATS) went to Kentucky and outlasted the Wildcats 45-42 win as a 1-point road fave.

The first move at TwinSpires was down to Georgia -20. The Bulldogs are getting 62% of spread tickets and 58% of spread money. The total initially dipped to 54.5, then rebounded to 56.

“Sharp play on Under 55,” Lucas said.

No. 2 Cincinnati at South Florida

The Cincinnati Bearcats mascot holds a sign in the second half of the NCAA football game
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Opening line: Cincinnati -23.5, Over/Under 58.5

UPDATE 3 P.M. ET THURSDAY: In a Friday night tilt, Cincinnati opened -23.5 at DraftKings and spent pretty much all week at -23. The Bearcats, in dire need of CFP style points, are taking 55% of spread bets and 70% of spread cash. The total fell from 58.5 to 57 by Wednesday afternoon, with ticket count 3/1 on the Over and money just shy of 2/1 on the Under.

Previous Cincinnati vs South Florida Odds Updates

UPDATE 3 P.M. ET MONDAY: Cincinnati is No. 2 in your AP poll but No. … 6 in your CFP rankings, meaning the Bearcats are on the outside looking in for the four-team playoff. Granted, Cincinnati will likely move to No. 5 in Tuesday night’s CFP update, thanks to Michigan State’s loss at Purdue.

Bottom line, though: Cincy has to pour on style points against weak opponents, then hope the Big Ten keeps cannibalizing itself or Oregon steps on a duck. However, the Bearcats (9-0 SU, 5-4 ATS) haven’t been gaining said style points lately. Cincinnati went off as favorites of 28.5, 27.5 and 22.5 points against Navy, Tulane and Tulsa, respectively, and failed to cover in all three.

In fact, Navy and Tulsa kept it within one score. In Week 10, Cincinnati got out to a 14-0 lead, then held off Tulsa 28-20.

TwinSpires initially fell back to Bearcats -23 for this Friday night American Athletic Conference contest against South Florida (2-7 SU, 5-3 ATS), then returned to -23.5 today. Cincy is taking 55% of tickets and the Bulls 56% of money.

“Good two-way action to start the week,” Lucas said.

The total is stable at 58.5, with the Over taking 57% of tickets/65% of money.

No. 4 Oklahoma at No. 18 Baylor

Oklahoma Sooners running back Kennedy Brooks runs against Kansas Jayhawks safety Kenny Logan Jr.
Image Credit: Jay Biggerstaff-USA TODAY Sports

Opening line: Oklahoma -6, Over/Under 63

UPDATE 8 P.M. ET FRIDAY: WynnBet opened the unbeaten Sooners as 5-point favorites and is now up to -6. Oklahoma is attracting 61% of spread tickets and 71% of spread money. The total dropped from 64 to 62, with ticket count almost 5/1 on the Over, but money running dead even.

Previous Oklahoma vs Baylor Odds Updates

UPDATE 3:30 P.M. ET THURSDAY: Oklahoma hit DraftKings’ odds board as a 6-point road chalk and on Monday morning dipped to -5.5, where it remains now. Baylor is actually getting the modest majority of tickets and money, at 53% and 54%, respectively. The total is down a point to 62, with ticket count 3/1 on the Over and money 2/1 on the Under.

UPDATE 3 P.M. ET MONDAY: Speaking of outside looking in, Oklahoma (9-0 SU, 4-5 ATS) is No. 4 in this week’s AP poll but No. 8 in the initial CFP rankings. Again, with CFP No. 3 Michigan State losing to Purdue, that’ll likely get the Sooners to No. 7 Tuesday night. But climbing three more spots will take more wins and some shakeups among the top six.

Oklahoma is coming off a bye, following a 52-21 beatdown of Texas Tech as a 19.5-point home favorite. Baylor (7-2 SU, 6-3 ATS) stubbed its toe in Week 10, falling 30-28 at Texas Christian as a 7.5-point road chalk. That said, the first move at TwinSpires was from Oklahoma -6 to -5.5, with 66% of tickets on the Sooners and 54% of money on the Bears.

“Sharp money on Baylor +6,” Lucas said.

The total crept up to 63.5, with 62% of tickets/60% of cash on the Over.

No. 9 Michigan at No. 23 Penn State

Penn State quarterback Sean Clifford looks downfield for an open receiver while holding the football
Image Credit: Scott Taetsch/Getty Images

Opening line: Penn State -1, Over/Under 48

UPDATE 8 P.M. ET FRIDAY: Michigan, aiming to keep CFP hopes alive, opened as a 1.5-point chalk at WynnBet and is now -1. Ticket count is just shy of 3/1 and money 2/1 on the Wolverines. The total upped from 47.5 to 48.5, with 59% of tickets/86% of cash on the Over.

Previous Michigan vs Penn State Odds Updates

UPDATE 3:30 P.M. ET THURSDAY: This line at DraftKings jumped the fence Tuesday from Penn State -1 to Michigan -1, and the Wolverines remain the slim fave today. Michigan is attracting 72% of bets and 80% of money on the spread. The total quickly dipped from 49 to 48, then stabilized at 48.5 Monday morning. Ticket count is just shy of 2/1 and money 4/1 on the Under.

UPDATE 3 P.M. ET MONDAY: Michigan (8-1 SU, 7-2 ATS) is trying to remain in the CFP conversation, sitting No. 7 in the rankings with a likely move to No. 6 Tuesday night. The Wolverines rebounded from their Week 9 loss at Michigan State by dusting Indiana 29-7 as 21-point home favorites Saturday.

Penn State (6-3 SU and ATS) just hopes to play Big Ten and CFP spoiler. The Nittany Lions beat Maryland 31-14 giving 10 points on the road in Week 10, a victory that pushed them back into the Top 25.

The Nittany Lions are up to -1.5  in college football Week 11 odds at TwinSpires, where 57% of bets are on Michigan and 55% of dollars on Penn State.

“Good two-way action, with some sharp play on Penn State -1,” Lucas said.

The total hasn’t moved, with 67% of bets/61% of dollars on the Under.

Mississippi State at No. 16 Auburn

Image Credit: Michael Chang-Getty Images

Opening line: Auburn -5.5, Over/Under 50

UPDATE 8 P.M. ET FRIDAY: Auburn opened as a 5-point favorite at WynnBet and is a 5-point fave tonight. The Tigers are landing 70% of spread bets and 72% of spread money. The total dipped from 52 to 50 this week on wildly varied splits, with 68% of tickets on the Over/96% of money on the Under.

Previous Mississippi State vs Auburn Odds Updates

UPDATE 3:30 P.M. ET THURSDAY: DraftKings has this line nailed to Auburn -5.5, not moving all week, save for the Tigers’ price spending time at -120 and -115. Auburn is now -5.5 flat, with ticket count just beyond 3/1 and money 6/1 on the home favorite. The total hasn’t budged off 50 on some intriguing splits: 55% of tickets on the Over, but 96% of money on the Under.

UPDATE 3 P.M. ET MONDAY: Auburn (6-3 SU, 5-4 ATS) was a sharp play at Texas A&M, but failed to show in a 20-3 loss catching 4.5 points. Mississippi State (5-4 SU and ATS) also fell in Week 10 but cashed for the third straight week and fourth time in five weeks, losing 31-28 at Arkansas as a 4-point underdog.

The line hasn’t moved, with Auburn netting 65% of early tickets and 55% of early cash. The total rose to 50.5, with the Over seeing 54% of tickets/60% of cash.

No. 7 Notre Dame at Virginia

Several unidentified Notre Dame players celebrate a touchdown
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Opening line: Notre Dame -4.5, Over/Under 64

UPDATE 5 P.M. ET SATURDAY: Notre Dame is now all the way up to -8 at TwinSpires Sportsbook, rising 1.5 points today alone and 3.5 points from the -4.5 opener. Ticket count is just shy of 2/1 and money 4/1 on the Fighting Irish. “Significant sharp play on Notre Dame,” TwinSpires trading analyst Zachary Lucas said, while noting the public, per usual, is also on the Irish. The total initially rose from 64 to 64.5, then dipped to 62.5, with 56% of tickets on the Over/54% of money on the Under.

Previous Notre Dame vs Virginia Odds Updates

UPDATE 8 P.M. ET FRIDAY: The Fighting Irish are down a notch to -5 from a -5.5 opening line at WynnBet. But this game is all Notre Dame on the spread, at 88% of tickets and 98% of money. The total made a sizable move over the last couple of hours, from the opener of 64.5 down to 63 on sharp Under play, according to WynnBet. The Over is getting 56% of tickets, while the Under is seeing 71% of money.

UPDATE 3:30 P.M. ET THURSDAY: Notre Dame is up to a 5.5-point favorite from a -4.5 opener at DraftKings, where action is heavy to the road favorite. Ticket count and money are both 6/1 on the Fighting Irish. The total fell from 65 to 64 in short order Sunday and hasn’t moved since, although the Over is drawing 71% of tickets/67% of dollars.

UPDATE 3 P.M. ET MONDAY: Notre Dame (8-1 SU, 6-3 ATS) has just one loss (at home vs. Cincinnati), but at No. 10 in the CFP rankings the Fighting Irish would need a ton of help to reach the playoff. That said, the Irish have won and covered four straight since that setback to the Bearcats. In Week 10, Notre Dame sank Navy 34-6 giving 21 points at home.

Virginia (6-3 SU and ATS) is off a bye after giving up a 60-plus burger at BYU, losing 66-49 as a 2.5-point ‘dog.

Notre Dame is already out to -5.5 at TwinSpires while catching 62% of spread tickets and 76% of spread money.

“A mix of public and sharp money on Notre Dame has pushed this line up,” Lucas said.

The total is up a half-point to 64.5, with 57% of tickets/66% of money on the Over.

No. 11 Texas A&M at No. 12 Mississippi

Texas A&M quarterback quarterback Zach Calzada (10) throws a pass in a game against Alabama
Image Credit: Gary Cosby Jr.-USA TODAY Sports

Opening line: Texas A&M -2, Over/Under 55.5

UPDATE 5 P.M. ET SATURDAY: Twinspires went from Texas A&M -2 to -2.5 early in the week, and the line pretty much stuck there the rest of the week. Ticket count and money are both running about 2/1 on the visiting Aggies. “We’ll need Ole Miss for a sizable amount,” TwinSpires trading analyst Zachary Lucas said. The total rose from 55.5 to 57.5, with 56% of tickets on the Over, but 64% of money on the Under.

Previous Texas A&M vs Mississippi Odds Updates

UPDATE 8:30 P.M. ET FRIDAY: WynnBet installed Texas A&M as a 2-point favorite at the outset and crept up to -2.5. Bettors are definitely on the short road chalk, with 78% of tickets and 92% of dollars on the Aggies. The total is up a point to 56.5, with 77% of tickets/60% of money on the Over.

UPDATE 3:30 P.M. ET THURSDAY: Texas A&M moved from -2 to -2.5 a couple of times early on at DraftKings and has stuck at -2.5 since Monday afternoon. Point-spread ticket count is 4/1 and money 3/1 on the Aggies. The total reached 57.5 this afternoon from a 55.5 opener, with 72% of tickets/71% of dollars on the Over.

UPDATE 3:30 P.M. ET MONDAY: Texas A&M has been on a roll since its big home upset of Alabama, which started an ongoing 4-0 SU and ATS run. In Week 10, the Aggies (7-2 SU, 6-3 ATS) stifled Auburn 20-3 as 4.5-point home faves. Meanwhile, Matt Corral and Mississippi (7-2 SU, 5-3-1 ATS) made me come #ChilisMoney … er, beat Liberty 27-14 giving 7.5 points at home.

Interestingly, A&M opened as 2-point road chalk and is up to -2.5 on TwinSpires’ college football Week 11 odds board. The Aggies are taking 71% of bets/67% of money.

“We’re already seeing a ton of handle on this game,” Lucas said. “It’ll likely be near the top [of Week 11] in terms of handle. The public is siding with A&M so far.”

The total is stable, with 62% of bets/63% of money on the Over.

No. 21 North Carolina State at No. 13 Wake Forest

Wake Forest Demon Deacons wide receiver A.T. Perry catches a touchdown pass as North Carolina Tar Heels defensive back Cam'Ron Kelly defends
Image Credit: Bob Donnan-USA TODAY Sports

Opening line: Wake Forest -2.5, Over/Under 66.5

UPDATE 5 P.M. ET SATURDAY: Wake Forest toggled between -2.5 and -2 a couple times by Friday night at TwinSpires, then dipped to -1 today. The Demon Deacons are landing 63% of spread bets and the Wolfpack 55% of spread dollars. “Sharp play on N.C. State +2.5,” TwinSpires trading analyst Zachary Lucas said. The total is down to 65 from a 66.5 opener, with the Under taking 58% of tickets/64% of cash.

Previous North Carolina State vs Wake Forest Odds Updates

UPDATE 8:30 P.M. ET FRIDAY: Wake Forest slipped from -2.5 to -2 at WynnBet, where ticket count is beyond 3/1 on the Demon Deacons, but money is almost 2/1 on the Wolfpack. And this is another total on the move tonight, dipping from 66.5 to 65 just in the past few hours on what WynnBet said was sharp Under play. Ticket count is almost dead even, at 51% on the Over, but 83% of cash is on the Under.

UPDATE 3:30 P.M. ET THURSDAY: Wake Forest opened as a 2.5-point fave at DraftKings and by Wednesday afternoon was down to -1. The Demon Deacons are now -1 (-120), while still taking 77% of bets and 66% of cash on the spread. The total is pinned to 66.5, with a ticket count of 2/1-plus and money 4/1-plus on the Over.

UPDATE 3:30 P.M. ET MONDAY: Wake Forest may yet win the ACC championship, but it’s clear that the ACC’s run of participating in all seven previous College Football Playoff events — almost entirely due to Clemson — is coming to a halt this season. The Demon Deacons (8-1 SU, 4-5 ATS) blew their slim CFP chances in a 58-55 loss at North Carolina as 2.5-point pups.

North Carolina State (7-2 SU, 6-3 ATS) bounced Florida State 28-14 as a 3-point road favorite in Week 10.

Wake Forest initially dipped to -2 at TwinSpires, then returned to -2.5, while taking 74% of tickets/58% of cash.

“Sharp money on both sides already, N.C. State +2.5 and Wake -2,” Lucas said. “This is another game seeing a lot of early action.”

The total hasn’t moved off 66.5, with 53% of tickets on the Under/56% of cash on the Over.