The 2025 NFL Week 14 Injury Report contains several key players who could significantly impact each team and the betting market.
Our analyst Juan Carlos Blanco analyzes the biggest names dealing with NFL Week 14 injuries.
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NFL Week 14 Injury Report: Key Players
Quarterback Injury News
Justin Herbert, Chargers, QUESTIONABLE (hand)
Herbert will attempt to suit up for Monday night’s game against the Eagles despite having just had surgery to stabilize a fracture in his left hand to start this week. Herbert suffered the injury in the Week 13 win over the Raiders and even missed several plays during the game, but he’s been able to put in a pair of limited practices to start prep for Week 14.
Herbert even took some snaps under center in Friday’s session, which is viewed as a significant step.
While it appears he’s setting himself up to play, the 2020 first-round pick could also be subbed out at times for Trey Lance, who completed his only pass for nine yards in relief of Herbert versus Las Vegas and is 7-for-13 for 90 yards overall this season across three appearances, in some under-center situations versus Philadelphia, such as short-yardage plays.
If Herbert ends up managing to handle the majority of plays from scrimmage and go through his throwing mechanics with minimal trouble, the Chargers offense and outlook for Los Angeles’ skill-position players should be largely unaffected.
Other notable short-term QB injuries: Justin Fields, Jets, OUT (knee)
Running Back Injuries
Alvin Kamara, Saints, OUT (knee)
Kamara will sit out his second game of the season against the Buccaneers on Sunday after once again missing practice all week due to his MCL injury. The veteran’s absence will afford rookie sixth-round pick Devin Neal, who garnered 69 total yards on 17 touches in Kamara’s stead against the Dolphins in Week 13, another week with the lead job.
Neal should only cede occasional touches to Evan Hull or Audric Estime, although the matchup against a Buccaneers defense surrenders just 3.81 RB yards per carry will be challenging all the way around.
Omarion Hampton, Chargers, QUESTIONABLE (IR, ankle)
Hampton is still on injured reserve as of Saturday morning but appears to be tracking for a return in Monday night’s game against the Eagles after turning in a full practice Friday. Hampton had also practiced on a limited basis in each of Los Angeles’ four prior sessions dating back to Week 13 prep, so he seems to be on the cusp of seeing his first action since Week 5.
If Hampton is indeed back in the fold versus Philadelphia, the Chargers may opt to ease him in considering backfield mate Kimani Vidal has averaged 75.0 rushing yards and 4.5 yards per carry over the last seven games as the starter, a stretch that includes a trio of 100-yard efforts.
Other notable short-term RB injuries to monitor: Emari Demercado, Cardinals, OUT (ankle); Dylan Sampson, Browns, QUESTIONABLE (calf)
Wide Receiver Injury News This Week
Marvin Harrison, Jr., Cardinals, OUT (heel)
Harrison was sidelined from practice all week due to a heel injury he suffered in his return from a two-game absence in Week 13 against the Buccaneers. His third absence in four games figures to once again be a boon for the outlook of No. 2 receiver Michael Wilson, who posted a 25-303-0 line on 33 targets during Harrison’s first two missed games.
However, Wilson could be even busier this week if game-script tilts a certain way against the Rams, as No. 3 wideout Greg Dortch, who posted a 12-119-2 tally on 15 targets during that same stretch, will also sit out due to a chest injury.
Tight end McBride, who had a 19-194-1 on 21 targets during Harrison’s first pair of games on the shelf, will also likely see a bump up from his already typically voluminous workload, and even Bam Knight and Michael Carter could be in line for more pass-catching work out of the backfield.
Drake London, Falcons, OUT (knee)
London will sit out a third straight game Sunday against the Seahawks after once again missing practice all week. As has been the case in his first two absences, London will be spelled by Darnell Mooney as the de facto No. 1 receiver versus Seattle, although that slotting has only led to a 5-99-1 line on eight targets for the veteran speedster through London’s first two absences.
Current No. 2 receiver David Sills, No. 3 Dylan Drummond, and tight end Kyle Pitts will also all theoretically be in line for more work, but the matchup against a ferocious Seahawks defense and quarterback Kirk Cousins’ spotty play keep expectations low overall for the air attack.
Rome Odunze, Bears, OUT (foot)
Odunze has been ruled out for Sunday’s critical divisional showdown against the Packers after missing practice all week with a lingering heel and foot issue that will finally cause his first absence of the season.
The Bears’ passing attack has been less than efficient on most weeks anyhow, but Odunze’s absence naturally does nothing to help the outlook for Caleb Williams. However, it will certainly improve the chances of a boost in opportunity for DJ Moore, Olamide Zaccheaus, and rookie Luther Burden.
The latter already had some buzz building around him before Odunze’s injury, as Burden sports a 13-157-0 line on 19 targets over the last four games, a stretch where he’s run 86 routes overall and has gotten a look from Williams at a 22.1% clip.
Meanwhile, Moore has seen his role decline this season – he’s averaging 5.0 targets per game after drawing 8.2 per contest in 2024 – but he’ll serve as the No. 1 receiver Sunday, albeit against a Packers defense surrendering just 159.7 passing yards per game in the last three.
Other notable short-term WR injuries to monitor: Greg Dortch, Cardinals, OUT (chest); Chris Olave, Saints, QUESTIONABLE (back); Jayden Reed, Packers, QUESTIONABLE (collarbone/foot); Joshua Palmer, Bills, QUESTIONABLE (knee); Matthew Golden, Packers, QUESTIONABLE (wrist); Parker Washington, Jaguars, QUESTIONABLE (hip); Xavier Weaver, Cardinals, QUESTIONABLE (hamstring)
Tight End Injuries
Dalton Kincaid, Bills, QUESTIONABLE (hamstring)
Kincaid was able to practice in a limited fashion all week, setting him up to potentially return from a three-game absence against the Bengals on Sunday. Dawson Knox and Jackson Hawes would be in line to once again spell Kincaid if he’s absent again, although the duo, with Knox the biggest beneficiary of the two so far in the form of back-to-back three-catch efforts.
Given the potential for a high-volume game for the passing attack against Joe Burrow and company, Buffalo’s versatile wideout corps might see the majority of any extra work stemming from a potential Kincaid absence primarily come their way.
Other notable short-term TE injuries to monitor: Michael Mayer, Raiders, OUT (ankle)
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