NFL Bets Today: Steelers vs Lions Predictions, Odds & Props (12/21)

We’ve got you covered for the best Steelers vs Lions predictions and player props for today! This is an unbelievably critical game for both teams, and we should see some fireworks in this one. This game has “season on the line” energy for both sides, and the market’s giving us plenty to work with on the spread, total, and player props.

Our NFL betting expert Justin Carlucci dives into the numbers. Let’s go.

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Steelers-Lions Preview and Predictions (12/21)

This Steelers vs Lions matchup checks every box for a high-variance, high-ceiling offensive game-script. There are plenty of mouthwatering spots to try and attack.

• Books have Detroit laying around a touchdown at home with a total in the low 50s, signaling real respect for this Lions offense.​
• Detroit is hanging top-tier scoring numbers (over 30 points per game) and ranks near the top of the league in red-zone TD rate, while the Steelers’ defense could yield much more time in the pocket without T.J. Watt​

Detroit’s defense is the wild card. The front has had strong stretches this season and can be disruptive, but the back end has been vulnerable, especially against elite receivers and accurate quarterbacks.

Losing safety Kerby Joseph to injured reserve coming into this week only magnifies those issues. Joseph had been a ball-hawking presence in the middle of the field, and his absence opens up windows for Rodgers to attack intermediate and deep between the numbers.

When all is said and done, the most likely story looks like Detroit’s offense sustaining drives and cashing in red-zone trips, while Pittsburgh answers in spurts behind Aaron Rodgers and DK Metcalf—but not often enough.

Steelers vs Lions Odds

• Spread: Lions -7.5 (-105)
• Moneyline: Steelers +315
• Game Total (O/U): 57.5

How to Watch Steelers vs. Lions

• Date: Sunday, December 21, 2025.​
• Kickoff: 4:25 p.m. ET.​
• Stadium: Ford Field, Detroit (indoor dome)
• ​​TV: NFL Sunday Ticket; Regional CBS Coverage

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Baker Mayfield TB QB TB @ CAR Live	o229.5 -113 u229.5 -111	o228.5 -137 u228.5 -137	o231.5 -112 u231.5 -112	o228.5 -144 u228.5 -113	o236.5 +110 u236.5 -145	o231.5 -121 u231.5 -112	o230.5 -115 u230.5 -115	o230.5 -137 u230.5 -137	-	-
Brady Cook NYJ QB NYJ @ NO Live	o167.5 -111 u167.5 -113	o167.5 -137 u167.5 -137	o169.5 -112 u169.5 -112	o166.5 -133 u166.5 -123	o164.5 -140 u164.5 +105	o168.5 -114 u168.5 -117	o165.5 -115 u165.5 -115	o170.5 -137 u170.5 -137	-	-
Bryce Young CAR QB TB @ CAR Live	o206.5 -112 u206.5 -112	o207.5 -137 u207.5 -137	o207.5 -112 u207.5 -112	o206.5 -126 u206.5 -129	o207.5 -115 u207.5 -115	o208.5 -120 u208.5 -112	o205.5 -120 u205.5 -110	o207.5 -137 u207.5 -137	-	-
Cameron Ward TEN QB KC @ TEN Live	o175.5 -113 u175.5 -111	o180.5 -137 u180.5 -137	o180.5 -112 u180.5 -112	o181.5 -128 u181.5 -128	o180.5 -115 u180.5 -115	o179.5 -118 u179.5 -113	o175.5 -115 u175.5 -115	o181.5 -137 u181.5 -137	-	-
Dak Prescott DAL QB LAC @ DAL Live	o253.5 -112 u253.5 -112	o250.5 -137 u250.5 -137	o249.5 -112 u249.5 -112	o252.5 -136 u252.5 -119	o256.5 -115 u256.5 -115	o253.5 -114 u253.5 -115	o250.5 -120 u250.5 -110	o254.5 -137 u254.5 -137	-	-
Gardner Minshew KC QB KC @ TEN Live	o214.5 -113 u214.5 -111	o212.5 -137 u212.5 -137	o212.5 -112 u212.5 -112	o213.5 -125 u213.5 -131	o221.5 -115 u221.5 -115	o215.5 -120 u215.5 -112	o210.5 -115 u210.5 -115	o212.5 -137 u212.5 -137	-	-
Jaxson Dart NYG QB MIN @ NYG Live	o189.5 -112 u189.5 -112	o191.5 -137 u191.5 -137	o191.5 -112 u191.5 -112	o195.5 -120 u195.5 -135	o193.5 -118 u193.5 -110	o190.5 -114 u190.5 -117	o190.5 -110 u190.5 -120	o197.5 -137 u197.5 -137	-	-
J.J. McCarthy MIN QB MIN @ NYG Live	o185.5 -111 u185.5 -113	o189.5 -137 u189.5 -137	o187.5 -112 u187.5 -112	o188.5 -135 u188.5 -121	o192.5 -115 u192.5 -115	o189.5 -114 u189.5 -115	o195.5 -110 u195.5 -120	o188.5 -137 u188.5 -137	-	-
Joe Burrow CIN QB CIN @ MIA Live	o260.5 -113 u260.5 -111	o260.5 -137 u260.5 -137	o259.5 -112 u259.5 -112	o259.5 -128 u259.5 -128	o263.5 -115 u263.5 -115	o261.5 -115 u261.5 -114	o255.5 -120 u255.5 -110	o258.5 -137 u258.5 -137	-	-
Josh Allen BUF QB BUF @ CLE Live	o210.5 -111 u210.5 -113	o208.5 -137 u208.5 -137	o207.5 -112 u207.5 -112	o216.5 -114 u216.5 -142	o211.5 -115 u211.5 -115	o208.5 -105 u208.5 -128	o200.5 -115 u200.5 -115	o211.5 -137 u211.5 -137	-	-
Justin Herbert LAC QB LAC @ DAL Live	o236.5 -112 u236.5 -112	o237.5 -137 u237.5 -137	o237.5 -112 u237.5 -112	o233.5 -133 u233.5 -123	o231.5 -115 u231.5 -115	o235.5 +100 u235.5 -135	o235.5 -110 u235.5 -120	o242.5 -137 u242.5 -137	-	-
Quinn Ewers MIA QB CIN @ MIA Live	o181.5 -112 u181.5 -112	o185.5 -137 u185.5 -137	o179.5 -112 u179.5 -112	o185.5 -125 u185.5 -131	o187.5 -115 u187.5 -115	o181.5 -121 u181.5 -111	o175.5 -120 u175.5 -110	o185.5 -137 u185.5 -137	-	-
Shedeur Sanders CLE QB BUF @ CLE Live	o178.5 -112 u178.5 -112	o180.5 -137 u180.5 -137	o177.5 -112 u177.5 -112	o179.5 -121 u179.5 -135	o180.5 -115 u180.5 -115	o178.5 -113 u178.5 -120	o175.5 -110 u175.5 -120	o180.5 -137 u180.5 -137	-	-
Tua Tagovailoa MIA QB CIN @ MIA Today 1:00 PM ET	o218.5 -112 u218.5 -112	o219.5 -137 u219.5 -137	o218.5 -114 u218.5 -114	o218.5 -125 u218.5 -131	o188.5 -115 u188.5 -115	o218.5 -115 u218.5 -115	o220.5 -110 u220.5 -120	o219.5 -137 u219.5 -137	-	-
Tyler Shough NO QB NYJ @ NO Live	o214.5 -113 u214.5 -111	o217.5 -137 u217.5 -137	o213.5 -112 u213.5 -112	o218.5 -126 u218.5 -129	o214.5 -115 u214.5 -115	o215.5 -125 u215.5 -110	o215.5 -110 u215.5 -120	o216.5 -137 u216.5 -137	-	-
Bo Nix DEN QB JAX @ DEN Today 4:05 PM ET	o241.5 -113 u241.5 -111	o244.5 -137 u244.5 -137	o240.5 -112 u240.5 -112	o236.5 -153 u236.5 -106	o244.5 -115 u244.5 -115	o241.5 -115 u241.5 -115	o240.5 -110 u240.5 -120	o242.5 -137 u242.5 -137	-	-
Jacoby Brissett ARI QB ATL @ ARI Live	o256.5 -112 u256.5 -112	o254.5 -137 u254.5 -137	o255.5 -112 u255.5 -112	o258.5 -131 u258.5 -125	o254.5 -115 u254.5 -115	o257.5 -127 u257.5 -107	o255.5 -115 u255.5 -115	o1.5 -137 u1.5 -137	-	-
Kirk Cousins ATL QB ATL @ ARI Live	o228.5 -111 u228.5 -113	o231.5 -137 u231.5 -137	o231.5 -112 u231.5 -112	o232.5 -128 u232.5 -128	o225.5 -115 u225.5 -118	o230.5 -114 u230.5 -115	o230.5 -110 u230.5 -120	o228.5 -137 u228.5 -137	-	-
Trevor Lawrence JAX QB JAX @ DEN Today 4:05 PM ET	o223.5 -113 u223.5 -111	o226.5 -137 u226.5 -137	o225.5 -112 u225.5 -112	o226.5 -123 u226.5 -131	o226.5 -115 u226.5 -115	o226.5 -114 u226.5 -115	o225.5 -120 u225.5 -110	o226.5 -137 u226.5 -137	-	-
Aaron Rodgers PIT QB PIT @ DET Live	o231.5 -113 u231.5 -112	o228.5 -137 u228.5 -137	o234.5 -112 u234.5 -112	o232.5 -131 u232.5 -125	o234.5 -115 u234.5 -115	o232.5 -115 u232.5 -114	o235.5 -115 u235.5 -115	o228.5 -137 u228.5 -137	-	-
C.J. Stroud HOU QB LV @ HOU Live	o227.5 -113 u227.5 -111	o227.5 -137 u227.5 -137	o227.5 -112 u227.5 -112	o231.5 -125 u231.5 -131	o221.5 -115 u221.5 -115	o226.5 -111 u226.5 -121	o225.5 -120 u225.5 -110	o227.5 -137 u227.5 -137	-	-
Geno Smith LV QB LV @ HOU Live	o184.5 -112 u184.5 -112	o179.5 -137 u179.5 -137	o180.5 -112 u180.5 -112	o179.5 -128 u179.5 -128	o186.5 -115 u186.5 -115	o183.5 -107 u183.5 -127	o180.5 -120 u180.5 -110	o182.5 -137 u182.5 -137	-	-
Jared Goff DET QB PIT @ DET Live	o269.5 -111 u269.5 -113	o265.5 -137 u265.5 -137	o267.5 -112 u267.5 -112	o261.5 -153 u261.5 -107	o270.5 -115 u270.5 -115	o268.5 -114 u268.5 -115	o265.5 -115 u265.5 -115	o1.5 -137 u1.5 -137	-	-
Drake Maye NE QB NE @ BAL Today 8:20 PM ET	o242.5 -113 u242.5 -111	o242.5 -137 u242.5 -137	o242.5 -112 u242.5 -112	o240.5 -156 u240.5 -106	o239.5 -115 u239.5 -115	o242.5 -127 u242.5 -107	o245.5 -110 u245.5 -120	o242.5 -137 u242.5 -137	-	-
Lamar Jackson BAL QB NE @ BAL Today 8:20 PM ET	o213.5 -112 u213.5 -112	o212.5 -137 u212.5 -137	o212.5 -112 u212.5 -112	o212.5 -120 u212.5 -135	o208.5 -115 u208.5 -115	o211.5 -114 u211.5 -115	o210.5 -115 u210.5 -115	o208.5 -137 u208.5 -137	-	-
Brock Purdy SF QB SF @ IND Tomorrow 8:15 PM ET	o246.5 -113 u246.5 -111	o248.5 -137 u248.5 -137	o243.5 -114 u243.5 -114	o242.5 -144 u242.5 -112	o249.5 -115 u249.5 -118	o244.5 -115 u244.5 -115	o245.5 -110 u245.5 -120	o243.5 -137 u243.5 -137	-	-
Philip Rivers IND QB SF @ IND Tomorrow 8:15 PM ET	o158.5 -112 u158.5 -112	o160.5 -137 u160.5 -137	o157.5 -114 u157.5 -114	o154.5 -144 u154.5 -112	o160.5 -115 u160.5 -115	o159.5 -120 u159.5 -112	o155.5 -125 u155.5 -105	o157.5 -137 u157.5 -137	-	-

Show All Showing 10 of 27

Last updated: Dec 21, 2025 5:42 PM | Showing 10 of 27 props

NFL Expert Picks: Steelers vs Lions Best Player Prop Bets

This could be the most exciting game of Week 16 from a points-scoring perspective. Check out some Steelers vs Lions props on Underdog:

PICK: Amon-Ra St. Brown> 85.5 Receiving Yards

The Steelers are giving up the 7th-highest catchable target rate and 10th-highest catch rate in the NFL, according to Fantasy Points. When the going gets tough in Detroit, Jared Goff always turns to ARSB. He should do it again in a great matchup and massive game total.

PICK: Jameson Williams > 69.5 Receiving Yards

Yes, I think you can play both of these guys. Williams has been incredible since Dan Campbell has taken over play-calling duties. His target rate rivals St. Brown’s (especially with Sam LaPorta out), and there’s a world where both of these guys go over these lines– and I think it’s reasonable.

Love running a pick’em slip back with Metcalf on it too, with the Steelers in catch-up mode.

Good luck!

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Looking for more content? We’ve got you covered all season:

• NFL News Hub
• Anytime Touchdown Scorers
• First Touchdown Scorers
• Rushing Props
• Receiving Props
• Monday Night Football Props
• Thursday Night Football Props
• Sunday Night Football Props
• NFL Week 16 Podscast
• Week 16 NFL Cheat Sheet